Lymph node metastasis (LNM) worsens the prognosis of nasopharyngeal cancer (NPC) patients. Thus, bioinformatic analysis was used to determine a key gene, the tyrosine-kinase receptor KITLG, that might play a critical rols in the LNM of NPC. The suppression of KITLG inhibits the proliferation, invasion, and metastasis of NPC cells via the JAK/STAT signaling pathway.
- Junjun Ling
- Liang Zhang
- Xianlu Zhuo