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Showing 1–6 of 6 results
Advanced filters: Author: Xiaoai Zhao Clear advanced filters

  • It is an exciting time for lipid metabolism and membrane cell biologists as technological progress has increased our ability to study lipids in cells. We asked leaders studying lipid cell biology from different perspectives to share what questions they are most interested in and what tools they believe the field is currently lacking.

    • Xiao-Wei Chen
    • Anthony S. Don
    • Yilong Zou
    Reviews
    Nature Cell Biology
    Volume: 27, P: 169-174

  • Measles virus hemagglutinin (MVH) can bind to different cell surface receptors in the human host. CD46, the first identified MVH receptor, is used mainly by vaccine strains, whereas clinical strains can use SLAM on macrophages and dendritic cells and nectin-4 on epithelial cells. The crystal structure of MVH in complex with the outermost ectodomain of nectin-4 is now presented, revealing a potential target site for drug development.

    • Xiaoai Zhang
    • Guangwen Lu
    • George F Gao
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 67-72

  • The crystal structure of the full-length human glucagon receptor reveals the essential role of the 12-residue ‘stalk’ segment and an extracellular loop in the regulation of ligand binding and receptor activation.

    • Haonan Zhang
    • Anna Qiao
    • Beili Wu
    Research
    Nature
    Volume: 546, P: 259-264