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Signal Transduction and Targeted Therapy (2)
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Showing 1–10 of 10 results

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H. pylori Escape Host Immunoreaction Through Inhibiting ILK Expression by VacA

Jianping Yuan
Ping Li
Xiaokui Guo
Research01 Jun 2009
Cellular & Molecular Immunology

Volume: 6, P: 191-197
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth

In this study, Cheng et al. show that ammonia released from glutaminolysis disrupts the SCAP–Insig association, thus activating SREBP-1 and promoting lipogenesis to support tumour growth

Chunming Cheng
Feng Geng
Deliang Guo
Research09 May 2022
Nature Metabolism

Volume: 4, P: 575-588
Safety assessment of Staphylococcus phages of the family Myoviridae based on complete genome sequences

Zelin Cui
Xiaokui Guo
Li Li
ResearchOpen Access24 Jan 2017
Scientific Reports

Volume: 7, P: 1-8
Stem cell transplantation extends the reproductive life span of naturally aging cynomolgus monkeys

Long Yan
Wan Tu
Hongmei Wang
ResearchOpen Access05 Nov 2024
Cell Discovery

Volume: 10, P: 1-17
Epidemiological and genetic charateristics of Vibrio vulnificus from diverse sources in China during 2012–2023

Isolated Vibrio vulnificus clones from various sources in China showed specific genomic markers linked to human pathogenesis, seafood, and migratory birds, these potentially may confer niche-specific advantages.

Dongling Long
Min Li
Yongzhang Zhu
ResearchOpen Access04 Jan 2025
Communications Biology

Volume: 8, P: 1-11
Carbapenem-resistant Escherichia coli exhibit diverse spatiotemporal epidemiological characteristics across the globe

Analysis of 7918 global carbapenem-resistant E. coli genomes reveals the transitions of diverse sequence types (STs), three host-switching events leading to the spread of resistance plasmids, and the crucial transmission country hubs and patterns of major STs.

Jiewen Huang
Chao Lv
Yongzhang Zhu
ResearchOpen Access06 Jan 2024
Communications Biology

Volume: 7, P: 1-13
Characterization of a small-molecule inhibitor targeting NEMO/IKKβ to suppress colorectal cancer growth

Zhenlong Yu
Jian Gao
Xiaochi Ma
ResearchOpen Access09 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-13
Whole genome sequencing revealed host adaptation-focused genomic plasticity of pathogenic Leptospira

Yinghua Xu
Yongzhang Zhu
Junzhi Wang
ResearchOpen Access02 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Correction: Characterization of a small-molecule inhibitor targeting NEMO/IKKβ to suppress colorectal cancer growth

Zhenlong Yu
Jian Gao
Xiaochi Ma
Amendments and CorrectionsOpen Access04 Sept 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1
Drug resistance and virulence of uropathogenic Escherichia coli from Shanghai, China

Yanchun Wang
Shengyuan Zhao
Ping He
Research02 Jul 2014
The Journal of Antibiotics

Volume: 67, P: 799-805