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Showing 51–100 of 120 results

Advanced filters: Author: Xiaoling Lin Clear advanced filters

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Carotid intima-media thickness (cIMT) and plaque are associated with subclinical atherosclerosis and coronary heart disease (CHD). Here, the authors identify and prioritize genetic loci for cIMT and plaque by GWAS and colocalization approaches and further demonstrate genetic correlation with CHD and stroke.

Nora Franceschini
Claudia Giambartolomei
Christopher J. O’Donnell
ResearchOpen Access03 Dec 2018
Nature Communications

Volume: 9, P: 1-14
MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation

MLL5 is an essential epigenetic modifier involved in cell cycle progression, chromatin architecture and hematopoiesis. Here the authors establish that MLL5 suppresses the innate immune response in a murine model of virus infection by targeting and promoting degradation of RIG-I.

Peipei Zhou
Xiaodan Ding
Yan Zhang
ResearchOpen Access28 Mar 2018
Nature Communications

Volume: 9, P: 1-13
Evolution of gene expression signature in mammary gland stem cells from neonatal to old mice

Xiaoling Huang
Yue Xu
Zuoren Yu
ResearchOpen Access12 Apr 2022
Cell Death & Disease

Volume: 13, P: 1-10
Enhancing urban resilience through machine learning-supported flood risk assessment: integrating flood susceptibility with building function vulnerability

Xiaoling Qin
Shifu Wang
Haochen Shi
ResearchOpen Access03 May 2025
npj Urban Sustainability

Volume: 5, P: 1-19
Non-Volatile Ferroelectric Switching of Ferromagnetic Resonance in NiFe/PLZT Multiferroic Thin Film Heterostructures

Zhongqiang Hu
Xinjun Wang
Nian X. Sun
ResearchOpen Access01 Sept 2016
Scientific Reports

Volume: 6, P: 1-8
Hypermethylated Epidermal growth factor receptor (EGFR) promoter is associated with gastric cancer

Xiaoling Weng
Hong Zhang
Yun Liu
ResearchOpen Access11 May 2015
Scientific Reports

Volume: 5, P: 1-10
Gait kinematic and kinetic characteristics among older adults with varying degrees of frailty: a cross-sectional study

Cai Jiang
Xiaoling Liu
Zhonghua Lin
ResearchOpen Access29 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination

Huang, Li, An, Yang, Cui et al. perform a single-cell multi-omics analysis of human spermatogenesis and identify a DNA demethylation event upon meiosis initiation, which is associated with meiotic recombination.

Yaping Huang
Lin Li
Xiao-Yang Zhao
Research18 Sept 2023
Nature Cell Biology

Volume: 25, P: 1520-1534
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

The next step after sequencing a genome is to figure out how the cell actually uses it as an instruction manual. A large international consortium has examined 1% of the genome for what part is transcribed, where proteins are bound, what the chromatin structure looks like, and how the sequence compares to that of other organisms.

Ewan Birney
John A. Stamatoyannopoulos
Pieter J. de Jong
Research14 Jun 2007
Nature

Volume: 447, P: 799-816
The innate interfacial elastic strain field of a transformable B2 precipitate embedded in an amorphous matrix

Xiaoling Fu
Yujun Lin
Robert O. Ritchie
ResearchOpen Access16 Dec 2023
npj Computational Materials

Volume: 9, P: 1-8
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

Long Yu and colleagues report a genome-wide association study for hepatitis B virus–related hepatocellular carcinoma (HBV-HCC). They report that genetic variants in STAT4 and HLA-DQ genes confer risk of HBV-HCC.

De-Ke Jiang
Jielin Sun
Long Yu
Research16 Dec 2012
Nature Genetics

Volume: 45, P: 72-75
A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability

Shan-Xiang Shen
Zoë Weaver
Chu-Xia Deng
Research17 Dec 1998
Oncogene

Volume: 17, P: 3115-3124
The value of intratumoral and peritumoral ultrasound radiomics model constructed using multiple machine learning algorithms for non-mass breast cancer

Jinhui Liu
Junjun Chen
Xiaoling Leng
ResearchOpen Access06 Jun 2025
Scientific Reports

Volume: 15, P: 1-14
DATS, the data tag suite to enable discoverability of datasets

Susanna-Assunta Sansone
Alejandra Gonzalez-Beltran
Lucila Ohno-Machado
ResearchOpen Access06 Jun 2017
Scientific Data

Volume: 4, P: 1-8
Social Dynamics of Science

Xiaoling Sun
Jasleen Kaur
Filippo Menczer
ResearchOpen Access15 Jan 2013
Scientific Reports

Volume: 3, P: 1-6
Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway

Yingbin Liu, Yun Liu, Hui Wang and colleagues perform whole-exome and targeted gene sequencing of gallbladder carcinoma. They identify recurrent somatic alterations in components of the ErbB signaling pathway and show that these alterations are associated with poor clinical outcomes.

Maolan Li
Zhou Zhang
Yingbin Liu
Research06 Jul 2014
Nature Genetics

Volume: 46, P: 872-876
Low doses of IFN-γ maintain self-renewal of leukemia stem cells in acute myeloid leukemia

Xiaoling Xie
Wuju Zhang
Xiaochun Bai
Research23 Oct 2023
Oncogene

Volume: 42, P: 3657-3669
Generation and comparative analysis of an Itga8-CreER^T2 mouse with preferential activity in vascular smooth muscle cells

Warthi et al. generated an alpha 8 integrin-cre driver that enables gene targeting preferentially in vascular smooth muscle cells (SMCs) and showed in a proof-of-principle study, that using the Itga8-CreER^T2 knock-in mouse for selective ablation of the Srf gene caused vascular defects but not a lethal visceral myopathy observed in an SMC-specific Myh11-CreER^T2-driven Srf loss.

Ganesh Warthi
Jessica L. Faulkner
Joseph M. Miano
Research11 Nov 2022
Nature Cardiovascular Research

Volume: 1, P: 1084-1100
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms

Gane Ka-Shu Wong
Bin Liu
HuanMing Yang
Research09 Dec 2004
Nature

Volume: 432, P: 717-722
Novel role for Ddx39 in differentiation and telomere length regulation of embryonic stem cells

Shanshan Nai
Meijie Wang
Lingyi Chen
Research06 Aug 2024
Cell Death & Differentiation

Volume: 31, P: 1534-1544
Automated diagnosis of adenoid hypertrophy with lateral cephalogram in children based on multi-scale local attention

Yanying Rao
Qiuyun Zhang
Shuli Xing
ResearchOpen Access10 Aug 2024
Scientific Reports

Volume: 14, P: 1-10
Reduced contrast sensitivity function and outer retina thickness in convalescent Vogt-Koyanagi-Harada disease

Yi-Sha Li
Xia Hu
Yu-Qin Wang
ResearchOpen Access08 Nov 2024
Eye

Volume: 39, P: 366-372
58-F, a flavanone from Ophiopogon japonicus, prevents hepatocyte death by decreasing lysosomal membrane permeability

Xiaofeng Yan
Tingjie Ye
Xiaoling Wang
ResearchOpen Access16 Jun 2016
Scientific Reports

Volume: 6, P: 1-15
Single cell-spatial transcriptomics and bulk multi-omics analysis of heterogeneity and ecosystems in hepatocellular carcinoma

Jiazhou Ye
Yan Lin
Rong Liang
ResearchOpen Access15 Nov 2024
npj Precision Oncology

Volume: 8, P: 1-18
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

Yinghao Sun and colleagues report a genome-wide association study for prostate cancer in Han Chinese men. They identify two new risk-associated loci at chromosomes 9q31 and 19q13.

Jianfeng Xu
Zengnan Mo
Yinghao Sun
Research30 Sept 2012
Nature Genetics

Volume: 44, P: 1231-1235
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Georg B. Ehret
Patricia B. Munroe
Toby Johnson
Research11 Sept 2011
Nature

Volume: 478, P: 103-109
IL-17RA/CTSK axis mediates H. pylori-induced castration-resistant prostate cancer growth

Guowen Lin
Feng Tian
Dingwei Ye
Research18 Oct 2024
Oncogene

Volume: 43, P: 3598-3616
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Joshua C. Bis
Xueqiu Jian
Lindsay A. Farrer
ResearchOpen Access14 Aug 2018
Molecular Psychiatry

Volume: 25, P: 1859-1875
Toripalimab plus chemotherapy for first line treatment of advanced non-small cell lung cancer (CHOICE-01): final OS and biomarker exploration of a randomized, double-blind, phase 3 trial

Jia Zhong
Kailun Fei
Jie Wang
ResearchOpen Access24 Dec 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-9
Carotid artery plaque intervention with Tongxinluo capsule (CAPITAL): A multicenter randomized double-blind parallel-group placebo-controlled study

Mei Zhang
Yan Liu
Yun Zhang
ResearchOpen Access14 Mar 2019
Scientific Reports

Volume: 9, P: 1-11
Unusual Inner-Salt Guaiazulene Alkaloids and bis-Sesquiterpene from the South China Sea Gorgonian Muriceides collaris

Pinglin Li
Xiaoling Liu
Guoqiang Li
ResearchOpen Access09 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
Dual Drug Loaded Biodegradable Nanofibrous Microsphere for Improving Anti-Colon Cancer Activity

Rangrang Fan
Xiaoling Li
Gang Guo
ResearchOpen Access21 Jun 2016
Scientific Reports

Volume: 6, P: 1-13
Magnetoelectric microelectromechanical and nanoelectromechanical systems for the IoT

Magnetoelectric (ME) microelectromechanical and nanoelectromechanical systems (M/NEMS) are vital for addressing the challenges of the internet of things (IoT) networks in size, energy efficiency and communication. This Review delves into ME materials and M/NEMS for IoT applications, such as sensing and communication technologies.

Bin Luo
A. R. Will-Cole
Nian X. Sun
Reviews07 May 2024
Nature Reviews Electrical Engineering

Volume: 1, P: 317-334
Celastrol ameliorates hypoxic-ischemic brain injury in neonatal rats by reducing oxidative stress and inflammation

Yingying Hu
Yan Nan
Zhenlang Lin
ResearchOpen Access20 May 2024
Pediatric Research

Volume: 96, P: 1681-1692
Financial inclusion, education, and employment: empirical evidence from 101 countries

Xiaoling Song
Jiaqi Li
Xueke Wu
ResearchOpen Access26 Jan 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-11
Small-molecule WNK inhibition regulates cardiovascular and renal function

A selective inhibitor of the With-No-Lysine (K) (WNK) kinase family reduces blood pressure and increases electrolyte excretion in hypertensive rats.

Ken Yamada
Hyi-Man Park
Lauren Monovich
Research05 Sept 2016
Nature Chemical Biology

Volume: 12, P: 896-898
Using 16S rDNA and metagenomic sequencing technology to analyze the fecal microbiome of children with avoidant/restrictive food intake disorder

Qina Ye
Shaodan Sun
Zhuoming Lu
ResearchOpen Access20 Nov 2023
Scientific Reports

Volume: 13, P: 1-15
Invariant community structure of soil bacteria in subtropical coniferous and broadleaved forests

Xiaoli Wang
Xiaoling Wang
Shenglei Fu
ResearchOpen Access12 Jan 2016
Scientific Reports

Volume: 6, P: 1-11
Integrated transcriptome and targeted metabolome analyses provide insights into flavonoid biosynthesis in kiwifruit (Actinidia chinensis)

Jipeng Mao
Zhu Gao
Lu Chen
ResearchOpen Access21 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
A critical epitope in CD147 facilitates memory CD4⁺ T-cell hyper-activation in rheumatoid arthritis

Na Guo
Sheng Ye
Ping Zhu
ResearchOpen Access21 Mar 2018
Cellular & Molecular Immunology

Volume: 16, P: 568-579
MicroRNA-129 modulates neuronal migration by targeting Fmr1 in the developing mouse cortex

Chao Wu
Xiaoling Zhang
Xiaozhong Peng
ResearchOpen Access25 Mar 2019
Cell Death & Disease

Volume: 10, P: 1-13
Effect of CHST11, a novel biomarker, on the biological functionalities of clear cell renal cell carcinoma

Weijing Hu
Yongquan Chen
Bo Wu
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-17
Targeting blood thrombogenicity precipitates atherothrombotic events in a mouse model of plaque destabilization

Xiaoling Liu
Mei Ni
Yun Zhang
ResearchOpen Access11 May 2015
Scientific Reports

Volume: 5, P: 1-12
A novel ADOA-associated OPA1 mutation alters the mitochondrial function, membrane potential, ROS production and apoptosis

Juanjuan Zhang
Xiaoling Liu
Min-Xin Guan
ResearchOpen Access18 Jul 2017
Scientific Reports

Volume: 7, P: 1-13
BPIFB1 inhibits vasculogenic mimicry via downregulation of GLUT1-mediated H3K27 acetylation in nasopharyngeal carcinoma

Xianjie Jiang
Xiangying Deng
Zhaoyang Zeng
Research01 Nov 2021
Oncogene

Volume: 41, P: 233-245
Exploration in the mechanism of fucosterol for the treatment of non-small cell lung cancer based on network pharmacology and molecular docking

Xiaoling Li
Baixin Lin
Lianxiang Luo
ResearchOpen Access01 Mar 2021
Scientific Reports

Volume: 11, P: 1-20
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice

Xiaoling Xu
Steven G Brodie
Chu-Xia Deng
Research13 Apr 2000
Oncogene

Volume: 19, P: 1868-1874
Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding

Xiaohua Tang
Rui Sun
Tiannan Guo
ResearchOpen Access25 Jul 2022
Cell Discovery

Volume: 8, P: 1-18
Analyses of Mitogenome Sequences Revealed that Asian Citrus Psyllids (Diaphorina citri) from California Were Related to Those from Florida

Fengnian Wu
Luci Kumagai
Xiaoling Deng
ResearchOpen Access31 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
α-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis

Kuo Liu
Ya Liu
Shaojun Wen
Research13 Jan 2011
Hypertension Research

Volume: 34, P: 389-399

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