The efficacy of cancer radio-immunotherapy is limited by the immunosuppressive tumor microenvironment. Here the authors report fusogenic liposomes loaded with Auranofin, a gold containing drug approved for rheumatoid arthritis, multivariate-gated aptamer assemblies and PD-L1 aptamers, as an adjuvant for melanoma-targeted radio-immunotherapy.
- Xijiao Ren
- Rui Xue
- Fudi Wang