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Showing 1–2 of 2 results
Advanced filters: Author: Xin-Ran Dong Clear advanced filters

  • LKB1 mutations have been associated with primary resistance to immune checkpoint inhibitors in patients with lung cancer. Here the authors show that Lkb1-deficient lung tumors are characterized by defective trafficking and adhesion of T cells and that, by upregulating ICAM1 expression, CDK4/6 inhibitors sensitize LKB1 mutant lung cancer to anti-PD1 blockade.

    • Xue Bai
    • Ze-Qin Guo
    • Zhong-Yi Dong
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Borospherenes are the boron-based analogs of fullerene cages. Here, the authors report a class of Ln3B18– metallo-borospherenes with unusual spherical trihedron geometry, in which the lanthanide atoms surprisingly form a part of the cage surface.

    • Teng-Teng Chen
    • Wan-Lu Li
    • Lai-Sheng Wang
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8