Stress stimulation-mediated liquid-liquid phase separation is an essential feature of living organisms, but its biophysical characteristics are poorly understood. Here, the authors report a UV-light stress stimulation behaviour in a binary community of synthetic protocells of condensates and proteinosomes, showing that condensates could behave like condensate pumps to enable a stepwise controlled transmembrane mass transfer regardless of the permeability barrier of proteinosomes.
- Yan Huang
- Haixu Chen
- Xin Huang