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Showing 1–3 of 3 results

Advanced filters: Author: Xinlai Qian Clear advanced filters

Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer

Zhu and colleagues identify GREMLIN1 as an FGFR1 ligand that promotes plasticity and castration resistance in prostate cancer through regulation of MAPK signaling, and show that anti-GREMLIN1 antibody therapy synergizes with androgen deprivation.

Chaping Cheng
Jinming Wang
Helen He Zhu
Research27 May 2022
Nature Cancer

Volume: 3, P: 565-580
PGRP-S promotes hepatocellular carcinoma progression via MAPK/ERK pathway by interaction with TTC1

Huifang Zhu
Shuang Feng
Xinlai Qian
ResearchOpen Access04 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
FMR1 promotes the progression of colorectal cancer cell by stabilizing EGFR mRNA in an m⁶A-dependent manner

Yuhan Hu
Qingzu Gao
Jiateng Zhong
ResearchOpen Access08 Nov 2022
Cell Death & Disease

Volume: 13, P: 1-14