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Egg-laying ChickenGTEx resource deciphers context-specific regulatory effects on fertility traits

Characterizing the genetic architecture underlying egg production is important for chicken breeding. Here, the authors integrate RNA and whole-genome sequencing data to better understand the genetic regulation of egg production in chickens.

Di Zhu
Kai Shi
Xiaoxiang Hu
ResearchOpen Access07 Dec 2025
Nature Communications

Volume: 17, P: 1-20
Plant immune response to pathogens differs with changing temperatures

Plants have two mechanisms to respond to infection; pattern-triggered immunity detects conserved microbial compounds, whereas effector-triggered immunity recognizes proteins secreted by pathogens. In this study, Cheng et al. report that temperature determines which of these immune systems is preferentially induced.

Cheng Cheng
Xiquan Gao
Ping He
Research26 Sept 2013
Nature Communications

Volume: 4, P: 1-9
TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton

Transcription activator-like effectors contribute to virulence of theXanthomonas strain responsible for bacterial blight in cotton. Here Cox et al. show that the XanthomonasAvrb6 effector induces expression of the cotton SWEET10 sugar transporter and that this induction promotes disease.

Kevin L. Cox
Fanhong Meng
Libo Shan
ResearchOpen Access24 May 2017
Nature Communications

Volume: 8, P: 1-14
Genetic regulation of gene expression across multiple tissues in chickens

This study introduces a ChickenGTEx atlas of regulatory variants across 28 tissues and illustrates its utility in deciphering association signals for 39 complex traits in chickens.

Dailu Guan
Zhonghao Bai
Lingzhao Fang
Research08 Apr 2025
Nature Genetics

Volume: 57, P: 1298-1308
Dynamic RBM47 ISGylation confers broad immunoprotection against lung injury and tumorigenesis via TSC22D3 downregulation

Shihui Ding
Xiquan Pang
Min Zhang
ResearchOpen Access30 Nov 2023
Cell Death Discovery

Volume: 9, P: 1-15

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Egg-laying ChickenGTEx resource deciphers context-specific regulatory effects on fertility traits

Plant immune response to pathogens differs with changing temperatures

TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton

Genetic regulation of gene expression across multiple tissues in chickens

Dynamic RBM47 ISGylation confers broad immunoprotection against lung injury and tumorigenesis via TSC22D3 downregulation

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