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Showing 1–5 of 5 results
Advanced filters: Author: Xiuhai Mao Clear advanced filters

  • The authors use a DNA-framework-based molecular classifier to perform biomarker panel screening and analyse six biomarkers across three-dimensional datatypes to obtain a molecular taxonomy for prostate cancer diagnosis.

    • Fangfei Yin
    • Haipei Zhao
    • Chunhai Fan
    Research
    Nature Nanotechnology
    Volume: 18, P: 677-686

  • Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.

    • Xiuhai Mao
    • Ke Li
    • Chao Zhong
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • DNA double helix exploiting Watson–Crick base-pairing lays the foundation of DNA nanotechnology. However, other forms of nucleic acids (e.g., triplex, i-motif, and G-quadruplex) exhibiting noncanonical base-base interactions bring about novel functionality. Here, we review the interplay of naturally occurring noncanonical nucleic acids and artificial DNA nanostructures in biomedical applications that have not been possible by duplex formation alone.

    • Shiliang He
    • Zhilei Ge
    • Xiuhai Mao
    ReviewsOpen Access
    NPG Asia Materials
    Volume: 13, P: 1-12