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Showing 1–2 of 2 results
Advanced filters: Author: Xue-Da Hu Clear advanced filters

  • Nasopharyngeal carcinoma is a diverse cancer characterised by a heterogeneous microenvironment. Here, the authors use single cell sequencing to analyse the tumour microenvironment in 10 nasopharyngeal carcinoma tumours and identify different cell types including immune-suppressive T regulatory, tolerogenic dendritic, and exhausted CD8 T cells.

    • Yang Liu
    • Shuai He
    • Jin-Xin Bei
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18

  • Jie He and colleagues report exome sequencing of 113 tumor-normal pairs of esophageal squamous cell carcinoma. They highlight mutations in genes involved in cell cycle and apoptosis regulation, histone modifier genes and genes encoding members of the Hippo and Notch pathways.

    • Yi-Bo Gao
    • Zhao-Li Chen
    • Jie He
    Research
    Nature Genetics
    Volume: 46, P: 1097-1102