Nature Search

The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis

Zhang and colleagues found that Omicron RBD binding to Siglec-9 impaired phagocytosis and antigen presentation in macrophages, an effect abrogated by an F375S mutation in the spike protein of Omicron.

Xin He
Xiantao Zhang
Hui Zhang
Research07 Mar 2024
Nature Immunology

Volume: 25, P: 622-632
Author Correction: PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense

Lulu Sun
Sijin Wu
Tianliang Li
Amendments and CorrectionsOpen Access11 Feb 2025
Nature Communications

Volume: 16, P: 1
Author Correction: Genomic analyses provide insights into spinach domestication and the genetic basis of agronomic traits

Xiaofeng Cai
Xuepeng Sun
Quanhua Wang
Amendments and CorrectionsOpen Access28 Jan 2022
Nature Communications

Volume: 13, P: 1
Genomic analyses provide insights into spinach domestication and the genetic basis of agronomic traits

Spinach is a nutritious leafy vegetable growing worldwide. Here, the authors report a high-quality chromosome-scale reference genome assembly of spinach and genome resequencing of 305 accessions, and provide insights into spinach domestication and the genetic basis of agronomic traits.

Xiaofeng Cai
Xuepeng Sun
Quanhua Wang
ResearchOpen Access13 Dec 2021
Nature Communications

Volume: 12, P: 1-12
Van der Waals polarity-engineered 3D integration of 2D complementary logic

We develop a method for high-density vertical stacking of active-device multi-layers, implementing memory and logic functions, using unique VIP-FETs where a van der Waals intercalation layer modulates the p- or n-type nature of the FETs.

Yimeng Guo
Jiangxu Li
Zheng Han
ResearchOpen Access29 May 2024
Nature

Volume: 630, P: 346-352
Phased diploid genome assemblies and pan-genomes provide insights into the genetic history of apple domestication

Phased diploid genomes of the cultivated apple Malus domestica cv. Gala and its two major wild progenitors M. sieversii and M. sylvestris, as well as pan-genome analyses, provide insights into the genetic history of apple domestication.

Xuepeng Sun
Chen Jiao
Zhangjun Fei
ResearchOpen Access02 Nov 2020
Nature Genetics

Volume: 52, P: 1423-1432
Genomes of cultivated and wild Capsicum species provide insights into pepper domestication and population differentiation

Existing genetics and genomics studies of peppers mainly focus on single species. Here, the authors report a pepper graph pan-genome and a genome variation map of 500 accessions from five domesticated species and close wild relatives to reveal their domestication, introgression and population differentiation.

Feng Liu
Jiantao Zhao
Xuexiao Zou
ResearchOpen Access07 Sept 2023
Nature Communications

Volume: 14, P: 1-14
PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense

The molecular mechanism of LAP activation against invading pathogens is not fully understood. Here the authors demonstrate that programmed cell death 6 (PDCD6) negatively regulates LAP formation and the antibacterial response by interacting with lactate dehydrogenase A (LDHA) to downregulate lactate metabolism and RUBCN lactylation-mediated signaling.

Lulu Sun
Sijin Wu
Tianliang Li
ResearchOpen Access23 Nov 2024
Nature Communications

Volume: 15, P: 1-20
The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

Nonalcoholic steatohepatitis (NASH) is a chronic liver disease with complex disease mechanisms. Here the authors report that the E3 ubiquitin-protein ligase Trim31 mitigates development of NASH via inhibition of rhomboid 5 homolog 2 (Rhbdf2) in mice.

Minxuan Xu
Jun Tan
Bochu Wang
ResearchOpen Access25 Feb 2022
Nature Communications

Volume: 13, P: 1-20
Publisher Correction: Chromatin analysis in human early development reveals epigenetic transition during ZGA

Jingyi Wu
Jiawei Xu
Yingpu Sun
Amendments and Corrections20 Jun 2018
Nature

Volume: 560, P: E27
Key role for CTCF in establishing chromatin structure in human embryos

The chromatin regulator CTCF has key roles in the gradual development of hierarchical chromatin structure during human embryogenesis.

Xuepeng Chen
Yuwen Ke
Zi-Jiang Chen
Research04 Dec 2019
Nature

Volume: 576, P: 306-310
Draft genome of spinach and transcriptome diversity of 120 Spinacia accessions

Spinach is an economically important vegetable crop but previous genomic resources were of limited use for comparative and functional analyses. Here, Xuet al. present a high quality draft spinach genome and transcriptome data for multiple Spinaciaaccessions providing insight into Caryophyllales genome evolution.

Chenxi Xu
Chen Jiao
Quanhua Wang
ResearchOpen Access24 May 2017
Nature Communications

Volume: 8, P: 1-10
The Torreya grandis genome illuminates the origin and evolution of gymnosperm-specific sciadonic acid biosynthesis

Torreya grandis is a gymnosperm species that produces edible seeds with high level of sciadonic acid (SCA). Here, the authors assemble the genome of this species, preform methylone analysis of seeds at different developmental stages, and reveal two key genes involved in SCA biosynthesis.

Heqiang Lou
Lili Song
Jiasheng Wu
ResearchOpen Access10 Mar 2023
Nature Communications

Volume: 14, P: 1-15
Structure of spinach photosystem II–LHCII supercomplex at 3.2 Å resolution

A high-resolution structural study sheds light on processes of energy transfer within the photosynthetic water-splitting machinery of plants.

Xuepeng Wei
Xiaodong Su
Zhenfeng Liu
Research18 May 2016
Nature

Volume: 534, P: 69-74
Spatiotemporal 3D chromatin organization across multiple brain regions during human fetal development

Yaoyu Sun
Min Li
Xuepeng Chen
ResearchOpen Access16 May 2025
Cell Discovery

Volume: 11, P: 1-15
Wheat microbiome bacteria can reduce virulence of a plant pathogenic fungus by altering histone acetylation

The molecular mechanisms behind the interactions between bacteria and fungi are largely unclear. Here, Chen et al. show that a compound secreted by bacteria from the wheat head microbiome inhibits growth and virulence of a plant pathogenic fungus by manipulating fungal histone modification.

Yun Chen
Jing Wang
Zhonghua Ma
ResearchOpen Access24 Aug 2018
Nature Communications

Volume: 9, P: 1-14
Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host

Only one of the three Taenia species causing taeniasis in humans was previously sequenced. Here the authors provide draft genomes of Taenia saginata and Taenia asiatica, analyse genome evolution of all three species, and identify potential targets for developing diagnostic markers or intervention tools.

Shuai Wang
Sen Wang
Xuepeng Cai
ResearchOpen Access22 Sept 2016
Nature Communications

Volume: 7, P: 1-12
Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment

Targeting histone acetylation modulators (HAMPs) is a promising avenue of drug discovery in cancer research. Here, the authors integrate multi-dimensional genomic profiles to systematically investigate recurrent genomic alterations in HAMPs, identifying potential therapeutic targets for precision epigenetic treatment.

Zhongyi Hu
Junzhi Zhou
Lin Zhang
ResearchOpen Access13 Feb 2019
Nature Communications

Volume: 10, P: 1-17
A CLE–SUNN module regulates strigolactone content and fungal colonization in arbuscular mycorrhiza

This study identifies the CLE peptides involved with the SUNN receptor in the autoregulation of the mycorrhizal symbiosis pathway during colonization of Medicago roots by arbuscular mycorrhizal fungi.

Lena M. Müller
Kristyna Flokova
Maria J. Harrison
Research02 Sept 2019
Nature Plants

Volume: 5, P: 933-939
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Melanoma cells release programmed death-ligand 1 (PD-L1) on the surface of circulating exosomes, suggesting a mechanism by which tumours could evade the immunesystem, and the potential application of exosomal PD-L1 to monitor patient responses to checkpoint therapies.

Gang Chen
Alexander C. Huang
Wei Guo
Research08 Aug 2018
Nature

Volume: 560, P: 382-386
RETRACTED ARTICLE: The diagnostic nomogram of platelet-based score models for hepatic alveolar echinococcosis and atypical liver cancer

Qiancheng Du
Yanyan Wang
Ying Zhou
ResearchOpen Access18 Dec 2019
Scientific Reports

Volume: 9, P: 1-9
Chromatin analysis in human early development reveals epigenetic transition during ZGA

By applying an optimized ATAC-seq protocol to human early embryos, distinct accessible chromatin landscapes are found before and after zygotic genome activation, revealing a marked epigenetic transition during zygotic genome activation and putative regulatory elements wiring human early development.

Jingyi Wu
Jiawei Xu
Yingpu Sun
Research02 May 2018
Nature

Volume: 557, P: 256-260
CHBP induces stronger immunosuppressive CD127⁺ M-MDSC via erythropoietin receptor

Jiawei Li
Guowei Tu
Ruiming Rong
ResearchOpen Access12 Feb 2021
Cell Death & Disease

Volume: 12, P: 1-12
Building material stocks and embodied carbon dataset for two urban agglomerations in China from 2000 to 2020

Hanwei Liang
Baizhe Zhang
Liang Dong
ResearchOpen Access02 Jun 2025
Scientific Data

Volume: 12, P: 1-11
Retraction Note: The diagnostic nomogram of platelet-based score models for hepatic alveolar echinococcosis and atypical liver cancer

Qiancheng Du
Yanyan Wang
Ying Zhou
Amendments and CorrectionsOpen Access29 Sept 2020
Scientific Reports

Volume: 10, P: 1
GBP2 facilitates the progression of glioma via regulation of KIF22/EGFR signaling

Yeqing Ren
Biao Yang
Zihan Zhou
ResearchOpen Access18 Apr 2022
Cell Death Discovery

Volume: 8, P: 1-9
Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations

Yali Qiao
Gefei Liu
Zhen Feng
ResearchOpen Access20 Aug 2018
Scientific Reports

Volume: 8, P: 1-10
Genomic and transcriptomic analyses of the tangerine pathotype of Alternaria alternata in response to oxidative stress

Mingshuang Wang
Xuepeng Sun
Hongye Li
ResearchOpen Access01 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
Comprehensive analysis of the GATA transcription factor gene family in breast carcinoma using gene microarrays, online databases and integrated bioinformatics

Shan Yu
Xuepeng Jiang
Baoliang Guo
ResearchOpen Access14 Mar 2019
Scientific Reports

Volume: 9, P: 1-16

Search

The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis

Author Correction: PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense

Author Correction: Genomic analyses provide insights into spinach domestication and the genetic basis of agronomic traits

Genomic analyses provide insights into spinach domestication and the genetic basis of agronomic traits

Van der Waals polarity-engineered 3D integration of 2D complementary logic

Phased diploid genome assemblies and pan-genomes provide insights into the genetic history of apple domestication

Genomes of cultivated and wild Capsicum species provide insights into pepper domestication and population differentiation

PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense

The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

Publisher Correction: Chromatin analysis in human early development reveals epigenetic transition during ZGA

Key role for CTCF in establishing chromatin structure in human embryos

Draft genome of spinach and transcriptome diversity of 120 Spinacia accessions

The Torreya grandis genome illuminates the origin and evolution of gymnosperm-specific sciadonic acid biosynthesis

Structure of spinach photosystem II–LHCII supercomplex at 3.2 Å resolution

Spatiotemporal 3D chromatin organization across multiple brain regions during human fetal development

Wheat microbiome bacteria can reduce virulence of a plant pathogenic fungus by altering histone acetylation

Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host

Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment

A CLE–SUNN module regulates strigolactone content and fungal colonization in arbuscular mycorrhiza

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

RETRACTED ARTICLE: The diagnostic nomogram of platelet-based score models for hepatic alveolar echinococcosis and atypical liver cancer

Chromatin analysis in human early development reveals epigenetic transition during ZGA

CHBP induces stronger immunosuppressive CD127⁺ M-MDSC via erythropoietin receptor

Building material stocks and embodied carbon dataset for two urban agglomerations in China from 2000 to 2020

Retraction Note: The diagnostic nomogram of platelet-based score models for hepatic alveolar echinococcosis and atypical liver cancer

GBP2 facilitates the progression of glioma via regulation of KIF22/EGFR signaling

Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations

Genomic and transcriptomic analyses of the tangerine pathotype of Alternaria alternata in response to oxidative stress

Comprehensive analysis of the GATA transcription factor gene family in breast carcinoma using gene microarrays, online databases and integrated bioinformatics

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