Nature Search

Schottky engineering of GDYO@Pt to boost piezoelectric and oxidative stress modulation for accelerated cranial regeneration

Electrical stimulation is known to aid bone repair, but ROS and hypoxia-induced oxidative stress can still impair repair. Here, the authors report on a piezoelectric semiconductor, developed to eliminate ROS, allow oxygen self-supply, and provide electrical stimulation to aid in stimulated bone repair.

Kang Song
Xuezheng Geng
Yubo Fan
ResearchOpen Access26 Sept 2025
Nature Communications

Volume: 16, P: 1-19
Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

The low throughput or content of current methods for the analysis of glycans-glycan binding proteins (GBPs) interactions hampers their clinical applications. Here, the authors conjugate synthesized glycans to Luminex beads to detect GBPs and apply it for the discovery of ovarian cancer biomarkers.

Sharad Purohit
Tiehai Li
Jin-Xiong She
ResearchOpen Access17 Jan 2018
Nature Communications

Volume: 9, P: 1-12
Recognition of microbial glycans by human intelectin-1

Extensive glycan microarray and structural analyses reveal that human intelectin-1 interacts selectively with microbial glycan epitopes through recognition of a terminal 1,2-diol group, an interaction that would be blocked in human glycans such as α-Neu5Ac.

Darryl A Wesener
Kittikhun Wangkanont
Laura L Kiessling
Research06 Jul 2015
Nature Structural & Molecular Biology

Volume: 22, P: 603-610
Oxidative release of natural glycans for functional glycomics

Treating glycoproteins with household bleach releases N- and O-glycans for further structural probing. Bleach treatment of glycosphingolipids releases glycan nitriles.

Xuezheng Song
Hong Ju
Richard D Cummings
Research02 May 2016
Nature Methods

Volume: 13, P: 528-534
Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo

Inhibiting the interaction between the membrane protein P-selectin and its ligand PSGL-1 is thought to block inflammation. Here the authors report an efficient stereoselective synthesis for PSGL-1 glycopeptide mimics and show that these compounds inhibit PSGL-1/P-selectin in vitro and in vivo.

Venkata R. Krishnamurthy
Mohammed Y. R. Sardar
Elliot L. Chaikof
Research31 Mar 2015
Nature Communications

Volume: 6, P: 1-12
Shotgun glycomics: a microarray strategy for functional glycomics

Derivatizing glycosphingolipids, extracted from bovine brain or human erythrocytes, with a fluorescent tag allows their immobilization on an array which can be probed with glycan binding proteins.

Xuezheng Song
Yi Lasanajak
David F Smith
Research05 Dec 2010
Nature Methods

Volume: 8, P: 85-90
Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells

Addition of a glycan precursor to cells results in the synthesis and secretion of a large variety of O-glycans that can be purified and biochemically analyzed to profile the cellular O-glycome.

Matthew R Kudelka
Aristotelis Antonopoulos
Tongzhong Ju
Research30 Nov 2015
Nature Methods

Volume: 13, P: 81-86
Streamlined gram-scale natural N-glycan production using reversible tagging after oxidative release of natural glycans

Glycoscience plays a crucial role in understanding cellular processes and disease mechanisms, but obtaining sufficient quantities of glycans for their functional analysis remains challenging. Here, the authors introduce a method for the large-scale preparation of natural N-glycans using 4-aminobenzoic acid-based tags.

Qing Zhang
Yi Lasanajak
Xuezheng Song
ResearchOpen Access04 Apr 2025
Communications Chemistry

Volume: 8, P: 1-12
Are optimistic CEOs and pessimistic CFOs the best partners? Evidence from corporate cash holdings

Huixiang Zeng
Limin Zheng
Linrong Chen
ResearchOpen Access13 Dec 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-19
Unique repertoire of anti-carbohydrate antibodies in individual human serum

Ralph N. D. Luetscher
Tanya R. McKitrick
Richard D. Cummings
ResearchOpen Access22 Sept 2020
Scientific Reports

Volume: 10, P: 1-15
Proof of concept for developing novel feeds for cattle from wasted food and crop biomass to enhance agri-food system efficiency

Zhengxia Dou
John D. Toth
Linda D. Baker
ResearchOpen Access10 Aug 2022
Scientific Reports

Volume: 12, P: 1-11

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Schottky engineering of GDYO@Pt to boost piezoelectric and oxidative stress modulation for accelerated cranial regeneration

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Recognition of microbial glycans by human intelectin-1

Oxidative release of natural glycans for functional glycomics

Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo

Shotgun glycomics: a microarray strategy for functional glycomics

Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells

Streamlined gram-scale natural N-glycan production using reversible tagging after oxidative release of natural glycans

Are optimistic CEOs and pessimistic CFOs the best partners? Evidence from corporate cash holdings

Unique repertoire of anti-carbohydrate antibodies in individual human serum

Proof of concept for developing novel feeds for cattle from wasted food and crop biomass to enhance agri-food system efficiency

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