Nature Search

Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells

Cheng-Ta Yang
Jhy-Ming Li
Miao-Fen Chen
ResearchOpen Access02 Dec 2008
Nature Precedings

P: 1
Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer

KRAS^G12D mutations frequently co-occur with mutated TP53 tumour suppressor in patients with pancreatic ductal adenocarcinoma (PDAC). Here the authors report the design of dual targeted therapeutic extracellular vesicles containing high copy numbers of TP53 mRNA and siKRAS^G12D, showing anti-tumor activity in PDAC preclinical models.

Chi-Ling Chiang
Yifan Ma
L. James Lee
ResearchOpen Access23 Oct 2023
Nature Communications

Volume: 14, P: 1-18
Motor cortex stimulation ameliorates parkinsonian locomotor deficits: effectual and mechanistic differences from subthalamic modulation

Lan-Hsin Nancy Lee
Chen Yuan Ngan
Chung-Chin Kuo
ResearchOpen Access19 Feb 2025
npj Parkinson's Disease

Volume: 11, P: 1-18
CMOS-integrated memristive non-volatile computing-in-memory for AI edge processors

A 1 Mb non-volatile computing-in-memory system, which integrates a resistive memory array with control and readout circuits using an established 65 nm foundry CMOS process, can offer high energy efficiency and low latency for Boolean logic and multiply-and-accumulation operations.

Wei-Hao Chen
Chunmeng Dou
Meng-Fan Chang
Research26 Aug 2019
Nature Electronics

Volume: 2, P: 420-428
Macrophage activation determines muscle wasting in pancreatic cancer

Chia-Jung Chang
Po-Hsien Huang
Yan-Shen Shan
ResearchOpen Access29 May 2025
Oncogene

Volume: 44, P: 2797-2813
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Nicotinamide N-methyltransferase (NNMT) expression is increased in white adipose tissue and liver of obese and diabetic mice, Nnmt knockdown protects against diet-induced obesity by altering the availability of adipose S-adenosylmethionine and NAD⁺, rendering Nnmt a novel target for treating obesity and type 2 diabetes.

Daniel Kraus
Qin Yang
Barbara B. Kahn
Research09 Apr 2014
Nature

Volume: 508, P: 258-262
Integrative Genome-Wide Association Studies of eQTL and GWAS Data for Gout Disease Susceptibility

Meng-tse Gabriel Lee
Tzu-Chun Hsu
Chien-Chang Lee
ResearchOpen Access21 Mar 2019
Scientific Reports

Volume: 9, P: 1-7
Deep brain stimulation rectifies the noisy cortex and irresponsive subthalamus to improve parkinsonian locomotor activities

Lan-Hsin Nancy Lee
Chen-Syuan Huang
Chung-Chin Kuo
ResearchOpen Access20 Jun 2022
npj Parkinson's Disease

Volume: 8, P: 1-18
Modulation of NMDA channel gating by Ca²⁺ and Cd²⁺ binding to the external pore mouth

Ya-Chi Tu
Ya-Chin Yang
Chung-Chin Kuo
ResearchOpen Access16 Nov 2016
Scientific Reports

Volume: 6, P: 1-16

Search

Filter By:

Search

Quick links