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Lactate regulates the YTHDF2-FTH1 axis to promote cardiomyocyte ferroptosis and aggravate myocardial ischemia-reperfusion injury

Zhonghao Xiang
Bitao Xiang
Chengliang Zhang
ResearchOpen Access08 Jan 2026
Scientific Reports

Volume: 16, P: 1-13
Feasibility study on cardiac resynchronization in the treatment of heart failure by single left bundle branch pacing

Yadong Du
Lijin Pu
Ling Zhao
ResearchOpen Access14 Dec 2023
Scientific Reports

Volume: 13, P: 1-10
The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation

Nelson et al. report that the APOE-R136S mutation protects against APOE4-promoted Alzheimer’s disease pathologies, including phosphorylated Tau accumulation, neuroinflammation and neurodegeneration, in mouse and human neuron models.

Maxine R. Nelson
Peng Liu
Yadong Huang
ResearchOpen Access13 Nov 2023
Nature Neuroscience

Volume: 26, P: 2104-2121
Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits

APOE4 is produced by neurons under stress, but the role of neuronal APOE4 in Alzheimer’s disease pathogenesis is still unclear. Here the authors report that selective removal of neuronal APOE4 in tauopathy mice mitigates many prominent Alzheimer’s disease-related pathologies.

Nicole Koutsodendris
Jessica Blumenfeld
Yadong Huang
ResearchOpen Access20 Feb 2023
Nature Aging

Volume: 3, P: 275-296
High-harmonic generation in Weyl semimetal β-WP₂ crystals

Weyl semimetals have interesting band-structure features that lead to unique properties. Here, the authors observe and study high-harmonic generation in type-II Weyl semimetal β-WP2 crystals.

Yang-Yang Lv
Jinlong Xu
Shining Zhu
ResearchOpen Access08 Nov 2021
Nature Communications

Volume: 12, P: 1-8
Metabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylation

The mechanisms regulating protein lactylation, a post-translational modification, are not fully understood. Here, the authors discover that Histone deacetylase 6 (HDAC6) acts as the primary lactyltransferase for α-tubulin, regulating microtubule dynamics.

Shuangshuang Sun
Zhe Xu
Lei Li
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-14
Voltage-controlled nonlinear optical properties in gold nanofilms via electrothermal effect

Here the authors demonstrate voltage-controlled nonlinear optical response of gold nanofilm via electrothermal effect. They fabricate a voltage-controlled saturable absorber for achieving wavelength-tunability/operation-regime switching in a fiber laser.

Changjian Lv
Fanchao Meng
Guanshi Qin
ResearchOpen Access29 Jul 2024
Nature Communications

Volume: 15, P: 1-12
Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion

Sun and colleagues describe that the secretion of interleukin-33 is dependent on a p40 N-terminal fragment of gasdermin D, whose generation is independent of inflammatory caspase-1 and caspase-11.

Wen Chen
Shuangfeng Chen
Bing Sun
Research06 Jul 2022
Nature Immunology

Volume: 23, P: 1021-1030
The Association of GSTM1 Deletion Polymorphism with Lung Cancer Risk in Chinese Population: Evidence from an Updated Meta-analysis

Haiyan Yang
Siyu Yang
Yadong Wang
ResearchOpen Access23 Mar 2015
Scientific Reports

Volume: 5, P: 1-8
ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma

Kai Wang
Deyu Guo
Jiajun Du
Research23 Apr 2024
Oncogene

Volume: 43, P: 1796-1810
Physics-informed neural networks for robust equivalent damping parameter inversion and fault diagnosis in gas-insulated switchgear vibration systems

Yuhang Li
Yuhui Lv
Yadong Liu
ResearchOpen Access08 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
N6-methyladenosine demethyltransferase FTO-mediated autophagy in malignant development of oral squamous cell carcinoma

Fang Wang
Yan Liao
Jinsong Hou
Research10 May 2021
Oncogene

Volume: 40, P: 3885-3898
Proper NADES treatment improved Zanthoxylum bungeanum essential oil yield and boosted α-terpineol antibacterial efficacy

Zhu Yadong
Zhang Chen
Zhao Hongfei
ResearchOpen Access14 May 2025
npj Science of Food

Volume: 9, P: 1-12
Lkb1 orchestrates γδ T-cell metabolic and functional fitness to control IL-17-mediated autoimmune hepatitis

Zhiqiang Xiao
Shanshan Wang
Meixiang Yang
Research19 Apr 2024
Cellular & Molecular Immunology

Volume: 21, P: 546-560
Synthesis of UV-resistant and colorless polyimide films for optoelectrical applications

Le Xi
Yadong Lv
Miqiu Kong
ResearchOpen Access11 Jan 2024
npj Materials Degradation

Volume: 8, P: 1-12
Research on the anti-ageing mechanism of Prunella vulgaris L.

Ping Li
Xiao Lv
Yadong Yang
ResearchOpen Access31 Jul 2023
Scientific Reports

Volume: 13, P: 1-9
mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation

Shuo Wan
Yadong Sun
Meixiang Yang
ResearchOpen Access11 Oct 2022
Cell Death & Disease

Volume: 13, P: 1-14
Author Correction: Single-nucleus profiling of adult mice sub-ventricular zone after blast-related traumatic brain injury

Manrui Li
Xiameng Chen
Weibo Liang
Amendments and CorrectionsOpen Access02 Oct 2023
Scientific Data

Volume: 10, P: 1
Single-nucleus profiling of adult mice sub-ventricular zone after blast-related traumatic brain injury

Manrui Li
Xiameng Chen
Weibo Liang
ResearchOpen Access05 Jan 2023
Scientific Data

Volume: 10, P: 1-9

Search

Lactate regulates the YTHDF2-FTH1 axis to promote cardiomyocyte ferroptosis and aggravate myocardial ischemia-reperfusion injury

Feasibility study on cardiac resynchronization in the treatment of heart failure by single left bundle branch pacing

The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation

Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits

High-harmonic generation in Weyl semimetal β-WP₂ crystals

Metabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylation

Voltage-controlled nonlinear optical properties in gold nanofilms via electrothermal effect

Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion

The Association of GSTM1 Deletion Polymorphism with Lung Cancer Risk in Chinese Population: Evidence from an Updated Meta-analysis

ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma

Physics-informed neural networks for robust equivalent damping parameter inversion and fault diagnosis in gas-insulated switchgear vibration systems

N6-methyladenosine demethyltransferase FTO-mediated autophagy in malignant development of oral squamous cell carcinoma

Proper NADES treatment improved Zanthoxylum bungeanum essential oil yield and boosted α-terpineol antibacterial efficacy

Lkb1 orchestrates γδ T-cell metabolic and functional fitness to control IL-17-mediated autoimmune hepatitis

Synthesis of UV-resistant and colorless polyimide films for optoelectrical applications

Research on the anti-ageing mechanism of Prunella vulgaris L.

mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation

Author Correction: Single-nucleus profiling of adult mice sub-ventricular zone after blast-related traumatic brain injury

Single-nucleus profiling of adult mice sub-ventricular zone after blast-related traumatic brain injury

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