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Showing 1–4 of 4 results

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Author Correction: Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation

Yaechan Song
Heeju Na
Han-Woong Lee
Amendments and CorrectionsOpen Access04 Jul 2024
Nature Communications

Volume: 15, P: 1
Ei24 deficiency in brown adipocytes induces severe hypothermia under cold stress independent of UCP1 activity

This study shows that loss of Ei24 in brown adipocytes disrupts mitochondrial function and leads to hypothermia under cold stress. The findings reveal a UCP1-independent mechanism of thermoregulation with implications for energy metabolism.

Su Bin Lee
Bui Thanh Thu
Han-Woong Lee
ResearchOpen Access01 Dec 2025
Nature Communications

Volume: 16, P: 1-17
Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation

The impact of obesity on cancer remains insufficiently explored. Here the authors show that in mouse models, dysfunctional adipocytes exhibit low levels of BECN1 which induce YAP/TAZ activity to promote breast and colorectal tumor progression.

Yaechan Song
Heeju Na
Han-Woong Lee
ResearchOpen Access14 May 2024
Nature Communications

Volume: 15, P: 1-16
Impaired AKT signaling and lung tumorigenesis by PIERCE1 ablation in KRAS-mutant non-small cell lung cancer

Jae-il Roh
Jaehoon Lee
Han-Woong Lee
ResearchOpen Access29 Jul 2020
Oncogene

Volume: 39, P: 5876-5887