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Showing 1–2 of 2 results
Advanced filters: Author: Yann Audic Clear advanced filters

  • The exon junction complex (EJC) has a crucial role in various post-transcriptional control mechanisms. CLIP-Seq analysis of the human EJC component eIF4AIII has revealed peaks in canonical EJC-binding regions, including ~24 nucleotides upstream of exon junctions. Surprisingly, EJCs are also present elsewhere in the transcriptome, uncovering an unexpected heterogeneity of EJC association with mRNAs.

    • Jérôme Saulière
    • Valentine Murigneux
    • Hervé Le Hir
    Research
    Nature Structural & Molecular Biology
    Volume: 19, P: 1124-1131