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Showing 1–2 of 2 results
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  • Genome-wide association studies (GWAS) have become a key tool to discover genetic markers for complex traits; however, environmental factors that interact with genes are rarely considered. Here, the authors conduct a GWAS of obesity traits, and find that smoking may alter genetic susceptibilities.

    • Anne E. Justice
    • Thomas W. Winkler
    • L Adrienne Cupples
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-19

  • Platelet aggregation is associated with myocardial infarction and stroke. Here, the authors have conducted a whole genome sequencing association study on platelet aggregation, discovering a locus in RGS18, where enhancer assays suggest an effect on activity of haematopoeitic lineage transcription factors.

    • Ali R. Keramati
    • Ming-Huei Chen
    • Andrew D. Johnson
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13