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Showing 1–9 of 9 results

Advanced filters: Author: Yik Weng Yew Clear advanced filters

Metabolic variation reflects dietary exposure in a multi-ethnic Asian population

In a large multi-ethnic Asian cohort, associations between over 1,000 plasma metabolites and specific foods and beverages are made. These diet–metabolite relationships were used to accurately predict clinical phenotypes such as diabetes and hypertension.

Dorrain Y. Low
Theresia H. Mina
John C. Chambers
Research17 Sept 2025
Nature Metabolism

Volume: 7, P: 1939-1954
Analysis of clinically relevant variants from ancestrally diverse Asian genomes

Clinically significant genetic variation in Asian populations is under-characterized. Here, the authors show the diversity in prevalence and spectrum of human disease and pharmacogenetic variants in a multi-ethnic Asian population.

Sock Hoai Chan
Yasmin Bylstra
Weng Khong Lim
ResearchOpen Access05 Nov 2022
Nature Communications

Volume: 13, P: 1-15
Investigating causal relationships between Body Mass Index and risk of atopic dermatitis: a Mendelian randomization analysis

Yik Weng Yew
Marie Loh
John C. Chambers
ResearchOpen Access17 Sept 2020
Scientific Reports

Volume: 10, P: 1-7
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function

Genome-wide association analyses of DNA methylation in peripheral blood from 3,799 Europeans and 3,195 South Asians identify unique SNP–CpG associations (meQTL), providing insights into molecular mechanisms and the potential links to phenotypic variation.

Johann S. Hawe
Rory Wilson
John C. Chambers
Research03 Jan 2022
Nature Genetics

Volume: 54, P: 18-29
Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort

Yik Weng Yew
Theresia Mina
Marie Loh
ResearchOpen Access21 Jul 2023
International Journal of Obesity

Volume: 47, P: 963-969
Factors influencing quality of life in children with atopic dermatitis and their caregivers: a cross-sectional study

Xiaomeng Xu
Louise Sandra van Galen
Josip Car
ResearchOpen Access05 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
Life stage impact on the human skin ecosystem: lipids and the microbial community

Martin P. Pagac
Bala Davient
Thomas L. Dawson Jr
ResearchOpen Access13 Jan 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-12
The relationships between sleep and adiposity amongst multi-ethnic Asian populations: a cross-sectional analysis of the Health for Life in Singapore (HELIOS) study

Chih Chiang Benjamin Lam
Theresia Mina
John C. Chambers
ResearchOpen Access19 Nov 2024
International Journal of Obesity

Volume: 49, P: 596-604
Association between exposure to ambient air pollution, meteorological factors and atopic dermatitis consultations in Singapore—a stratified nationwide time-series analysis

Diyar Mailepessov
Janet Ong
Yik Weng Yew
ResearchOpen Access06 May 2024
Scientific Reports

Volume: 14, P: 1-11