Axonal maintenance is known to rely, in part, on non-cell-autonomous support from myelinating glia, but the mechanisms are still unclear. In this study, the authors show that loss of the serine/threonine kinase LKB1 in Schwann cells leads to changes in nerve metabolism and axonal degeneration, even in the absence of demyelination.
- Bogdan Beirowski
- Elisabetta Babetto
- Jeffrey Milbrandt
