Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Ying-Yin Chao Clear advanced filters

  • Gasdermin E pore formation has been associated with pyroptotic cell death. Here the authors identify gasdermin E pores in a subset of human TH17 cells and show that rather than killing these cells the pores enable the release of IL-1α on NLRP3 inflammasome activation as an antifungal immune response.

    • Ying-Yin Chao
    • Alisa Puhach
    • Christina E. Zielinski
    ResearchOpen Access
    Nature Immunology
    Volume: 24, P: 295-308

  • Dimethyl fumarate (DMF) is a therapy for multiple sclerosis (MS) with undetermined mechanism of action. Here the authors find that clinical response to DMF associates with decrease in IL-17-producing CD8+ T cells (Tc17), delineate molecular pathways involved, and show that DMF suppresses Tc17 pathogenicity in a mouse model of MS.

    • Christina Lückel
    • Felix Picard
    • Magdalena Huber
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15