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Showing 1–4 of 4 results
Advanced filters: Author: Yizi Mao Clear advanced filters
  • Long-read chromatin assay reveals (1) a novel class of accessible chromatin regions, (2) accessibility within individual LTR retrotransposons and (3) the relationship between diffuse accessibility, gene body methylation and hAT transposon insertion.

    • Kerry L. Bubb
    • Morgan O. Hamm
    • Christine Queitsch
    Research
    Nature Plants
    Volume: 11, P: 1181-1192
  • Simultaneous profiling of the genome, methylome, epigenome and transcriptome using single-molecule chromatin fiber sequencing and multiplexed arrays isoform sequencing identifies the genetic and molecular basis of an undiagnosed Mendelian disease case with an X;13-balanced translocation.

    • Mitchell R. Vollger
    • Jonas Korlach
    • Andrew B. Stergachis
    Research
    Nature Genetics
    Volume: 57, P: 469-479
  • The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

    • Tim H. H. Coorens
    • Ji Won Oh
    • Yuqing Wang
    Reviews
    Nature
    Volume: 643, P: 47-59
  • Wang et al. analyze the metabolome and lipidome of heart and plasma samples from patients with HCM and healthy individuals and identify panels of metabolites that can be used as diagnostic biomarkers of HCM or predictors of HCM patient survival; patients are stratified into three groups with distinct cardiac function and survival and identify metabolic pathways that are greatly affected in patients with HCM, suggesting that targeting the pentose phosphate pathway and oxidative stress may represent effective ways to treat HCM.

    • Wenmin Wang
    • Jizheng Wang
    • Zeping Hu
    Research
    Nature Cardiovascular Research
    Volume: 1, P: 445-461