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Showing 1–2 of 2 results
Advanced filters: Author: Yoh-ichi Kawabe Clear advanced filters
  • The acetyltransferase MYST1 stimulated by acetyl-CoA, and the deacetylase SIRT2 stimulated by NAD+, regulate PAX7 acetylation in muscle stem cells, which in turn, regulates stem cell self-renewal and regeneration following injury in mouse skeletal muscle.

    • Marie-Claude Sincennes
    • Caroline E. Brun
    • Michael A. Rudnicki
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15
  • The ubiquitin ligase CHIP suppresses tumour growth and metastasis in breast cancer, and its expression inversely correlates with malignancy. The role of CHIP in cancer depends on degradation of the transcriptional co-activator SRC-3, which regulates expression of Smad and Twist.

    • Masashi Kajiro
    • Ryuichi Hirota
    • Junn Yanagisawa
    Research
    Nature Cell Biology
    Volume: 11, P: 312-319