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Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality.

Yong-Bin Wang
Sheng-Cai Zheng
Bin Tan
ResearchOpen Access19 May 2017
Nature Communications

Volume: 8, P: 1-9
Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

Axially chiral compounds have proven to be privileged catalysts/ligands for asymmetric catalysis, with BINOL, SPNIOL and their derivatives being particularly successful. Here the authors report a family of axially chiral alkenes, and demonstrate their use in asymmetric catalysis.

Yong-Bin Wang
Peiyuan Yu
Bin Tan
Research03 Jun 2019
Nature Catalysis

Volume: 2, P: 504-513
Catalytic atroposelective synthesis

Atropisomerism is an expanding target of asymmetric catalysis. In this Review, recent advances in atroposelective synthesis under catalytic control are highlighted with a focus on general strategies that provide high versatility and modularity.

Shao-Hua Xiang
Wei-Yi Ding
Bin Tan
Reviews30 Apr 2024
Nature Catalysis

Volume: 7, P: 483-498
Ancient DNA from nomads in 2500-year-old archeological sites of Pengyang, China

Yong-Bin Zhao
Hong-Jie Li
Hui Zhou
Research26 Feb 2010
Journal of Human Genetics

Volume: 55, P: 215-218
Correction: RIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signaling

Ying Mei
Yong-Bin Liu
Hong-Hao Zhou
Amendments and CorrectionsOpen Access27 Aug 2021
Cell Death & Disease

Volume: 12, P: 1-2
Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

Danni Lyu
Lifang Zhang
Ke Yao
ResearchOpen Access01 Oct 2021
npj Regenerative Medicine

Volume: 6, P: 1-14
RIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signaling

Ying Mei
Yong-Bin Liu
Hong-Hao Zhou
ResearchOpen Access20 Sept 2018
Cell Death & Disease

Volume: 9, P: 1-17
GRK5 functions as an oncogenic factor in non-small-cell lung cancer

Li-Ping Jiang
Song-Qing Fan
Yong-Bin Chen
ResearchOpen Access20 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-12
Improved drought tolerance in wheat plants overexpressing a synthetic bacterial cold shock protein gene SeCspA

Tai-Fei Yu
Zhao-Shi Xu
You-Zhi Ma
ResearchOpen Access10 Mar 2017
Scientific Reports

Volume: 7, P: 1-14
A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase

Huihui Liu
Yan-Song Gao
Haipeng Gong
ResearchOpen Access16 Feb 2016
Scientific Reports

Volume: 6, P: 1-12

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Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

Rational design, enantioselective synthesis and catalytic applications of axially chiral EBINOLs

Catalytic atroposelective synthesis

Ancient DNA from nomads in 2500-year-old archeological sites of Pengyang, China

Correction: RIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signaling

Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

RIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signaling

GRK5 functions as an oncogenic factor in non-small-cell lung cancer

Improved drought tolerance in wheat plants overexpressing a synthetic bacterial cold shock protein gene SeCspA

A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase

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