Methylation of DNA CpG motifs is modulated in part by the TET family of epigenetic regulators. Aifantis and colleagues show that loss of TET1 function biases hematopoiesis toward the B cell lineage and promotes hematopoietic malignancies.
- Luisa Cimmino
- Meelad M Dawlaty
- Iannis Aifantis
