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Experimental & Molecular Medicine (5)
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Showing 1–8 of 8 results

Advanced filters: Author: Yoon-Seong Kim Clear advanced filters

An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models

An optimized agonist of Nurr1, 4A7C-301, protects dopamine neurons against environmental and genetic risk factors of Parkinson’s disease (PD) in vitro, and improves both motor and non-motor deficits in male rodent models of PD.

Woori Kim
Mohit Tripathi
Kwang-Soo Kim
ResearchOpen Access18 Jul 2023
Nature Communications

Volume: 14, P: 1-17
Celastrol inhibits production of nitric oxide and proinflammatory cytokines through MAPK signal transduction and NF-κB in LPS-stimulated BV-2 microglial cells

Hyo Won Jung
Yoo Sun Chung
Yong-Ki Park
ResearchOpen Access01 Dec 2007
Experimental & Molecular Medicine

Volume: 39, P: 715-721
Protein kinase A-dependent phosphorylation of B/K protein

Hemin Chin
Sung-Ho Choi
Oh-Joo Kwon
ResearchOpen Access01 Apr 2006
Experimental & Molecular Medicine

Volume: 38, P: 144-152
Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease

Yoon Seong Kim
Tong H Joh
ReviewsOpen Access01 Aug 2006
Experimental & Molecular Medicine

Volume: 38, P: 333-347
Transcriptional mutagenesis by 8-oxodG in α-synuclein aggregation and the pathogenesis of Parkinson’s disease

Sambuddha Basu
Goun Je
Yoon-Seong Kim
ReviewsOpen Access28 Aug 2015
Experimental & Molecular Medicine

Volume: 47, P: e179
A single-nuclei paired multiomic analysis of the human midbrain reveals age- and Parkinson’s disease–associated glial changes

Aging is a risk factor of Parkinson’s disease (PD). Adams, Song et al. present a multiomics analysis of the human midbrain showing age-induced changes in genes associated with glial function, with further alterations of oligodendrocytes in PD.

Levi Adams
Min Kyung Song
Yoon-Seong Kim
Research15 Mar 2024
Nature Aging

Volume: 4, P: 364-378
Induction of unfolded protein response during neuronal induction of rat bone marrow stromal cells and mouse embryonic stem cells

Yoon Mi Cho
Yoon-Seong Jang
Oh-Joo Kwon
ResearchOpen Access26 Jun 2009
Experimental & Molecular Medicine

Volume: 41, P: 440-452
A novel tool for monitoring endogenous alpha-synuclein transcription by NanoLuciferase tag insertion at the 3′end using CRISPR-Cas9 genome editing technique

Sambuddha Basu
Levi Adams
Yoon-Seong Kim
ResearchOpen Access04 Apr 2017
Scientific Reports

Volume: 7, P: 1-11