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Showing 1–2 of 2 results
Advanced filters: Author: Yoshifumi Okochi Clear advanced filters

  • Structural and functional analysis reveal the resting state of the voltage-gated proton channel Hv1. Comparison with structures of voltage-sensing domains from other systems, captured in the activated state, will aid in understanding the mechanism of voltage sensing.

    • Kohei Takeshita
    • Souhei Sakata
    • Atsushi Nakagawa
    Research
    Nature Structural & Molecular Biology
    Volume: 21, P: 352-357

  • In the dimeric voltage-gated H+channel, Hv1/VSOP, the gating of each subunit is coupled, but the molecular basis of dimer formation and intersubunit coupling is unclear. This study shows that channel assembly and cooperative gating are mediated by the cytoplasmic domain.

    • Yuichiro Fujiwara
    • Tatsuki Kurokawa
    • Yasushi Okamura
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-11