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Showing 1–4 of 4 results

Advanced filters: Author: Yoshiki Omatsu Clear advanced filters

Parallel fabrication of spiral surface structures by interference pattern of circularly polarized beams

Yoshiki Nakata
Masataka Yoshida
Noriaki Miyanaga
ResearchOpen Access07 Sept 2018
Scientific Reports

Volume: 8, P: 1-9
Ebf3⁺ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells

CAR cells act as HSC niche cells. Here the authors show that CXCL12 ablation in half CAR cells attracts HSCs from affected CAR cells to intact CAR cells whereas CXCL12 ablation in all CAR cells depletes balanced HSCs producing B cells at high levels.

Taichi Nakatani
Tatsuki Sugiyama
Takashi Nagasawa
ResearchOpen Access25 Oct 2023
Nature Communications

Volume: 14, P: 1-12
Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells

The transcription factors, Runx1 and Runx2 are critical embryonically for generation of HSCs and osteoblasts, respectively. Here the authors show that adult mice lacking Runx1 and Runx2 in HSC-supporting CAR cells displayed an increase in fibrosis with reduced HSCs in bone marrow.

Yoshiki Omatsu
Shota Aiba
Takashi Nagasawa
ResearchOpen Access12 May 2022
Nature Communications

Volume: 13, P: 1-12
Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation

Transcription factor Foxc1 is a key regulator of haematopoietic stem/progenitor cell niche formation.

Yoshiki Omatsu
Masanari Seike
Takashi Nagasawa
Research02 Mar 2014
Nature

Volume: 508, P: 536-540