Non-nucleotide stimulators of interferon gene (STING) agonists hold great promise as the immunotherapeutic agents for cancer therapy. Here, this group reports incorporating STING agonist MSA-2 and DOX in the separate layers of 3D-printed polymeric scaffold for effectively activating STING-IFNβ pathway, enhancing DAMPs release thereby suppressing postsurgical tumor recurrence and metastasis.
- Kai Li
- Xuan Yu
- Mingqiang Li
