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Showing 1–12 of 12 results
Advanced filters: Author: Yuchuan Miao Clear advanced filters
  • Somitoids and segmentoids—culture systems that recapitulate the formation of somite-like structures—reveal that an initial salt-and-pepper expression pattern of MESP2 in a newly formed segment is transformed into compartments of anterior and posterior identity through an active cell-sorting mechanism.

    • Yuchuan Miao
    • Yannis Djeffal
    • Olivier Pourquié
    Research
    Nature
    Volume: 614, P: 500-508
  • Different membrane proteins dynamically polarize to organize signal transduction, but the underlying mechanism is unclear. Here, the authors show that a differential diffusion mediated partitioning process is sufficient to drive such spatiotemporal patterning of membrane-associated signaling proteins.

    • Tatsat Banerjee
    • Satomi Matsuoka
    • Pablo A. Iglesias
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-24
  • How chromatin-associated RNAs (caRNAs) are spatially organized in the context of the multiscale genome architecture is unclear. Here the authors suggest how the 3D genome architecture can modulate the spatial distribution of caRNAs at different scales, and how in turn caRNA could affect the dynamic 3D genome organization.

    • Riccardo Calandrelli
    • Xingzhao Wen
    • Sheng Zhong
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14
  • Banerjee et al. detail the spatial and temporal dynamics of the surface charge on the inner leaflet of the plasma membrane and show that these dynamics are necessary and sufficient to regulate signalling pathways mediating cell migration and polarity.

    • Tatsat Banerjee
    • Debojyoti Biswas
    • Peter N. Devreotes
    Research
    Nature Cell Biology
    Volume: 24, P: 1499-1515
  • A model of the embryonic human trunk attains a more mature developmental stage than previous models.

    • Yuchuan Miao
    • Olivier Pourquié
    News & Views
    Nature Biotechnology
    Volume: 42, P: 1185-1186
  • Somite formation, crucial for organization of the segmental pattern of vertebrate embryos, depends on the oscillatory expression of segmentation clock genes. Novel in vitro models of somitogenesis have provided insights into the spatiotemporal dynamics of gene expression, signalling and metabolic gradients that enable somite formation and patterning.

    • Yuchuan Miao
    • Olivier Pourquié
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 25, P: 517-533