Background interference signals from normal tissues compromise the sensitive fluorescence imaging of early disease tissues with exogenous probes in vivo. Here, the authors report a Near-infrared-II excited ‘’off-on-off” fluorescent probe to focus on events occurring on the diffusion of the activated probes from cancer tissues to normal tissues for imaging of early orthotopic liver tumors.
- Yufu Tang
- Yuanyuan Li
- Bin Liu
