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Advanced filters: Author: Yuhee Chung Clear advanced filters

Hypercompact adenine base editors based on a Cas12f variant guided by engineered RNA

A hypercompact adenine base editor termed TaRGET-ABE was developed by fusing a catalytically inactive transposon-associated transposase B guided by an engineered RNA to deaminases, which achieves efficient A-to-G conversions via adeno-associated viral delivery in mammalian genomes.

Do Yon Kim
Yuhee Chung
Yong-Sam Kim
Research01 Aug 2022
Nature Chemical Biology

Volume: 18, P: 1005-1013
Author Correction: Hypercompact adenine base editors based on a Cas12f variant guided by engineered RNA

Do Yon Kim
Yuhee Chung
Yong-Sam Kim
Amendments and Corrections16 Feb 2023
Nature Chemical Biology

Volume: 19, P: 389
Auxin Response Factors promote organogenesis by chromatin-mediated repression of the pluripotency gene SHOOTMERISTEMLESS

The pluripotency factor SHOOTMERISTEMLESS (STM) maintains stem cell identity in the centre of the shoot apical meristem. Here Chung et al. show that Auxin Response Factors work in concert with the YABBY transcription factor FIL to silence STM via chromatin modifications and allow initiation of primordia that lead to formation of flowers.

Yuhee Chung
Yang Zhu
Doris Wagner
ResearchOpen Access21 Feb 2019
Nature Communications

Volume: 10, P: 1-11

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