Nature Search

AI-Assisted detection of corneal nerve structural abnormalities in early diabetic keratopathy: development and validation of a deep learning framework

Jiali Pan
Xiaoshuo Shi
Yanning Yang
ResearchOpen Access20 Jan 2026
Scientific Reports

Volume: 16, P: 1-11
Oxidative [4+2] annulation of styrenes with alkynes under external-oxidant-free conditions

A sequence of a Diels–Alder reaction and oxidation is a powerful route to valuable aromatic compounds. Here, the authors report a more atom-economical oxidant-free strategy involving a Diels–Alder with H₂ evolution under noble-metal-free photoredox conditions.

Guoting Zhang
Yulin Lin
Aiwen Lei
ResearchOpen Access26 Mar 2018
Nature Communications

Volume: 9, P: 1-7
UFL1 triggers replication fork degradation by MRE11 in BRCA1/2-deficient cells

The mechanisms of stalled fork degradation in BRCA1/2-deficient cells remain unclear. UFL1, an UFM1-specific E3 ligase, was found to catalyze PTIP UFMylation at lysine 148, promoting stalled fork degradation by the MRE11 nuclease.

Tian Tian
Junliang Chen
Ting Liu
Research22 Apr 2024
Nature Chemical Biology

Volume: 20, P: 1650-1661
A lineage-resolved cartography of microRNA promoter activity in C. elegans empowers multidimensional developmental analysis

By tracing promoter expression in lineage-mapped single cells, Xu et al. present a whole-body cartography of microRNA transcriptional activities during C. elegans embryogenesis and demonstrate its broad utility in multifaceted functional analyses.

Weina Xu
Jinyi Liu
Zhuo Du
ResearchOpen Access30 Mar 2024
Nature Communications

Volume: 15, P: 1-23
Nlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates

The emergence of hematopoietic stem and progenitor cells is finely tuned by a variety of signaling pathways. Here, the authors find that Nlrc3 is highly expressed during hematopoietic differentiation in vivo and in vitro, activates the Notch pathway, and acts downstream of NF-kB signaling.

Shuyang Cai
Honghu Li
He Huang
ResearchOpen Access03 Jan 2024
Nature Communications

Volume: 15, P: 1-16
A metabolic atlas of blood cells in young and aged mice identifies uridine as a metabolite to rejuvenate aged hematopoietic stem cells

Zeng, Shi, Han, Hu, Li, Wei et al. present a metabolic atlas covering 15 hematopoietic cell types from young and aged mice. By screening metabolites that are depleted with age, they identify that uridine treatment can restore function in aged hematopoietic stem cells.

Xiangjun Zeng
Ce Shi
He Huang
Research17 Jul 2024
Nature Aging

Volume: 4, P: 1477-1492
Information technology assists in the innovative development of throwing embroidered balls

Shijun Xu
Yu Wei
Fanhui Xu
ResearchOpen Access19 Apr 2025
Scientific Reports

Volume: 15, P: 1-14
Real-time predictive model of extrauterine growth retardation in preterm infants with gestational age less than 32 weeks

Liang Gao
Wei Shen
Xiaohong Liu
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-13
ELTD1 inhibits differentiation of hemogenic endothelium progenitors from human embryonic stem cells through the HPIP–Wnt pathway

Qian Luo
Yijin Chen
He Huang
ResearchOpen Access02 Jun 2025
Experimental & Molecular Medicine

Volume: 57, P: 1216-1231
An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease

Yue Zhao
Chunhong Wang
Youhua Liu
ResearchOpen Access12 Jun 2018
Scientific Reports

Volume: 8, P: 1-14
The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells

Mengjia He
Qianni Jin
Tingmei Chen
Research09 Apr 2019
Oncogene

Volume: 38, P: 5551-5565

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AI-Assisted detection of corneal nerve structural abnormalities in early diabetic keratopathy: development and validation of a deep learning framework

Oxidative [4+2] annulation of styrenes with alkynes under external-oxidant-free conditions

UFL1 triggers replication fork degradation by MRE11 in BRCA1/2-deficient cells

A lineage-resolved cartography of microRNA promoter activity in C. elegans empowers multidimensional developmental analysis

Nlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates

A metabolic atlas of blood cells in young and aged mice identifies uridine as a metabolite to rejuvenate aged hematopoietic stem cells

Information technology assists in the innovative development of throwing embroidered balls

Real-time predictive model of extrauterine growth retardation in preterm infants with gestational age less than 32 weeks

ELTD1 inhibits differentiation of hemogenic endothelium progenitors from human embryonic stem cells through the HPIP–Wnt pathway

An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease

The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells

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