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Showing 1–4 of 4 results

Advanced filters: Author: Yusuke Ohsawa Clear advanced filters

Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist

Sphingosine 1-phosphate receptor 1 (S1PR1) is crucial for lymphocyte trafficking and a target in inflammatory diseases. Here, authors discover KSI6666, a competitive S1PR1 antagonist that suppresses inflammation through pseudoirreversible inhibition.

Yuya Maruyama
Yusuke Ohsawa
Taishin Akiyama
ResearchOpen Access19 Jul 2024
Nature Communications

Volume: 15, P: 1-17
Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer

Hiromi Sakamoto
Kimio Yoshimura
Setsuo Hirohashi
Research18 May 2008
Nature Genetics

Volume: 40, P: 730-740
Molecular hydrogen attenuates gefitinib-induced exacerbation of naphthalene-evoked acute lung injury through a reduction in oxidative stress and inflammation

Yasuhiro Terasaki
Tetsuya Suzuki
Ikuroh Ohsawa
Research01 Feb 2019
Laboratory Investigation

Volume: 99, P: 793-806
Circulating TNF Receptors 1 and 2 Predict Mortality in Patients with End-stage Renal Disease Undergoing Dialysis

Tomohito Gohda
Shuntaro Maruyama
Yusuke Suzuki
ResearchOpen Access03 Mar 2017
Scientific Reports

Volume: 7, P: 1-10