Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–13 of 13 results
Advanced filters: Author: Yuval Elani Clear advanced filters

  • Scientists are captivated by the prospect of creating a fully synthetic cell, offering the potential to revolutionize biology, medicine and biotechnology. In this Viewpoint, a panel of experts discusses the definitions of a synthetic cell and highlights current achievements, challenges and future opportunities of building such systems.

    • Katarzyna P. Adamala
    • Marileen Dogterom
    • T-Y Dora Tang
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 25, P: 162-167

  • Matryoshka doll-like, nested vesicles, each containing a different ingredient to a chemical reaction, can serve as microreactors. Here, the authors developed a system in which mixing of the ingredients can be induced by irradiation with ultraviolet light.

    • James W. Hindley
    • Yuval Elani
    • Oscar Ces
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-6

  • RNA-based genetic regulation has been used to control protein translation in synthetic cells in response to the external temperature. RNA thermometers enable in situ protein expression above permissive temperatures. Controlled expression of the membrane pore α-hemolysin allows small-molecule cargo to be released in a temperature-dependent manner.

    • Carolina Monck
    • Yuval Elani
    • Francesca Ceroni
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 20, P: 1380-1386

  • Most lipid nanoparticles are structurally simplistic, existing as single-compartment assemblies. Now, a microfluidic technology to create liposomes-in-liposomes—with full control over particle features, such as the composition of each membrane, the intermembrane distance and payload of each compartment—has been developed. These particles are exploited for multi-stage release and in situ enzymatic synthesis within the particle’s attolitre volume.

    • Colin P. Pilkington
    • Ignacio Gispert
    • Yuval Elani
    ResearchOpen Access
    Nature Chemistry
    Volume: 16, P: 1612-1620

  • Assembly of higher-order artificial vesicles can unlock new applications. Here, the authors use optical tweezers to construct user-defined 2D and 3D architectures of chemically distinct vesicles and demonstrate inter-vesicle communication and light-enabled compartment merging.

    • Guido Bolognesi
    • Mark S. Friddin
    • Yuval Elani
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • A common genetic cause of Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is expansion of the intronic hexanucleotide repeat (GGGGCC)n in C9orf72. Here the authors reveal that the RNA (GGGGCC)n expansion repeat associated with ALS/FTD can generate condensates in the absence of proteins, highlighting the potential relevance of targeting RNA-structures to treat neurodegenerative diseases.

    • Federica Raguseo
    • Yiran Wang
    • Marco Di Antonio
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Bio-mimetic motion has been hard to achieve due to a lack of biocompatible conditions. Here, the authors report the creation of a liposome-stabilised aqueous PEG/dextran Pickering-like emulsion system with motion induced by the Marangoni effect and characterised by negative chemotaxis.

    • Shaobin Zhang
    • Claudia Contini
    • Oscar Ces
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Hydrogels have been found to replicate the gel-like properties of many intracellular environments and are thus of great interest in the construction of artificial cells. This Review highlights how hydrogels are currently used and explores avenues for their use in the construction of next-generation artificial cells.

    • Matthew E. Allen
    • James W. Hindley
    • Yuval Elani
    Reviews
    Nature Reviews Chemistry
    Volume: 6, P: 562-578

  • Liquid domains can coexist within lipid membranes, and directly manipulating them in situ may offer a useful tool. Here optical tweezers are used to directly move liquid-ordered domains within the lipid bilayers of individual giant vesicles.

    • Mark S. Friddin
    • Guido Bolognesi
    • Yuval Elani
    ResearchOpen Access
    Communications Chemistry
    Volume: 2, P: 1-7