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Advanced filters: Author: Zachary A. Shalit Clear advanced filters

Repurposing of glatiramer acetate to treat cardiac ischemia in rodent models

Sarig and Tzahor et al. show that the multiple sclerosis drug glatiramer acetate improves cardiac function and reduces scar area in rodent models of acute myocardial infarction and ischemic heart failure.

Gal Aviel
Jacob Elkahal
Rachel Sarig
Research26 Aug 2024
Nature Cardiovascular Research

Volume: 3, P: 1049-1066
A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ

Many natural-product like drugs have a tetracyclic terpenoid core. Here, the authors developed a synthesis of triterpene-like tetracyclic systems, and apply this method to the preparation of a number of enantiomeric compounds, two of which are very selective ligands for estrogen receptor beta

Wan Shin Kim
Zachary A. Shalit
Glenn C. Micalizio
ResearchOpen Access04 Jun 2019
Nature Communications

Volume: 10, P: 1-10
Genetic and phylogenetic analysis of dissimilatory iodate-reducing bacteria identifies potential niches across the world’s oceans

Victor Reyes-Umana
Zachary Henning
John D. Coates
ResearchOpen Access02 Jul 2021
The ISME Journal

Volume: 16, P: 38-49