Nature Search

Relationship between mean platelet volume and metabolic syndrome in Chinese patients

Fengxiao Zhao
Ziyu Yan
Wan Zhang
ResearchOpen Access01 Oct 2018
Scientific Reports

Volume: 8, P: 1-6
Serum midkine as a surrogate biomarker for metastatic prediction in differentiated thyroid cancer patients with positive thyroglobulin antibody

Qiang Jia
Zhaowei Meng
Chunmei Zhang
ResearchOpen Access27 Feb 2017
Scientific Reports

Volume: 7, P: 1-7
Decoding the genomic landscape of chromatin-associated biomolecular condensates

The authors develop CondSigDetector, a computational framework designed to detect condensate-like chromatin-associated protein co-occupancy signatures, to predict genomic loci and component proteins of distinct chromatin-associated biomolecular condensates.

Zhaowei Yu
Qi Wang
Yong Zhang
ResearchOpen Access13 Aug 2024
Nature Communications

Volume: 15, P: 1-16
CerS6 links ceramide metabolism to innate immune responses in diabetic kidney disease

Disturbed lipid metabolism is a feature of diabetic kidney disease (DKD). Here the authors report that ceramide synthase 6 (CerS6) in podocytes contributes to the pathogenesis of diabetic kidney disease (DKD) in male mice by inducing mitochondrial DNA leakage, activating the cGAS-STING pathway and promoting inflammation.

Zijing Zhu
Yun Cao
Zhaowei Chen
ResearchOpen Access11 Feb 2025
Nature Communications

Volume: 16, P: 1-20
BacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases

Prime editing in bacteria is currently inefficient. Here the authors report BacPE, a versatile prime editing platform in Escherichia coli that works by inhibiting 3′→5′ DNA exonucleases, highlighting the intrinsic genetic factors that are adverse to efficient prime editing.

Hongyuan Zhang
Jiacheng Ma
Quanjiang Ji
ResearchOpen Access27 Jan 2024
Nature Communications

Volume: 15, P: 1-9
Association between liver function and metabolic syndrome in Chinese men and women

Sen Wang
Jie Zhang
Qiyu Jia
ResearchOpen Access20 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Molecular basis and engineering of miniature Cas12f with C-rich PAM specificity

Most miniature Cas12f nucleases have T-rich PAM specificity, restricting their targeting scopes. The cryo-EM structure of the Clostridium novyi Cas12f1 reveals the molecular basis for rare C-rich PAM recognition and enables optimization of sgRNA scaffold to improve CnCas12f1 activity.

Mengjiao Su
Fan Li
Quanjiang Ji
Research11 Sept 2023
Nature Chemical Biology

Volume: 20, P: 180-189
Composition and phase engineering of metal chalcogenides and phosphorous chalcogenides

A competitive-chemical-reaction-based growth mechanism by controlling the kinetic parameters can easily realize the growth of transition metal chalcogenides and transition metal phosphorous chalcogenides with different compositions and phases.

Jiadong Zhou
Chao Zhu
Zheng Liu
Research23 Jun 2022
Nature Materials

Volume: 22, P: 450-458
Phase engineering of Cr₅Te₈ with colossal anomalous Hall effect

Few-nanometre-thick flakes of trigonal and monoclinic Cr₅Te₈ can be grown using chemical vapour deposition, with the monoclinic phase exhibiting an anomalous Hall conductivity of 650 Ω^–1 cm^–1 and anomalous Hall angle of 5%.

Bijun Tang
Xiaowei Wang
Zheng Liu
Research25 Apr 2022
Nature Electronics

Volume: 5, P: 224-232
Restrictive blood transfusion strategies and associated infection in orthopedic patients: a meta-analysis of 8 randomized controlled trials

Zhaowei Teng
Yun Zhu
Xiguang Zhang
ResearchOpen Access26 Aug 2015
Scientific Reports

Volume: 5, P: 1-7
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Tumor–normal paired DNA samples from a breast cancer cell line and a matched lymphoblastoid cell line enable calibration of clinical sequencing pipelines and benchmarking ‘tumor-only’ or ‘matched tumor–normal’ analyses.

Li Tai Fang
Bin Zhu
Yuanting Zheng
Research09 Sept 2021
Nature Biotechnology

Volume: 39, P: 1151-1160
STING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury

Yun Cao
Xinghua Chen
Zhaowei Chen
ResearchOpen Access14 Mar 2024
Cell Death & Disease

Volume: 15, P: 1-13
Proteome-wide mendelian randomization identifies novel therapeutic targets for chronic kidney disease

Pin Zhao
Zhenhao Li
Xuepei Zhang
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
Effects of different KRAS mutants and Ki67 expression on diagnosis and prognosis in lung adenocarcinoma

Jun Wang
Liwen Dong
Pan Li
ResearchOpen Access19 Feb 2024
Scientific Reports

Volume: 14, P: 1-11
A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis

Qi Yan et al. find that JNK-associated leucine zipper protein (Jlp) counteracts the profibrotic effects of TGF-β1 and autophagy on renal tubular epithelial cells and that TGF-β1 and FGF-2 can negatively regulate the expression of Jlp. These findings provide insights into the role of Jlp in kidney fibrosis.

Qi Yan
Kai Zhu
Huiming Wang
ResearchOpen Access05 Jun 2020
Communications Biology

Volume: 3, P: 1-16
ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L

Weijie Zhang
Ruochen Zhang
Jian-an Huang
ResearchOpen Access31 Jul 2021
Cell Death & Disease

Volume: 12, P: 1-11
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction

Hui Yang
Yuhu He
Shenghua Zhou
ResearchOpen Access26 Nov 2020
Cell Death & Disease

Volume: 11, P: 1-16
Label-free Quantitative Analysis of Protein Expression Alterations in miR-26a-Knockout HeLa Cells using SWATH-MS Technology

Hexiao Shen
Li Li
Lixin Ma
ResearchOpen Access04 Feb 2019
Scientific Reports

Volume: 9, P: 1-13
Alteration of N6-methyladenosine epitranscriptome profiles in bilateral ureteral obstruction-induced obstructive nephropathy in juvenile rats

Jinjin Feng
Yanping Zhang
Xuepei Zhang
Research19 Aug 2022
Pediatric Research

Volume: 93, P: 1509-1518

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