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Advanced filters: Author: Zhi-Jing Xu Clear advanced filters
  • Metformin is a medication for type 2 diabetes but little is known about the fate of metformin by microbial catabolism. Here the authors characterize a Ni2 + -dependent heterohexameric enzyme MetCaCb from the ureohydrolase superfamily, catalyzing the hydrolysis of metformin into guanylurea and dimethylamine.

    • Tao Li
    • Zhi-Jing Xu
    • Ning-Yi Zhou
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10