Peptide aldehydes are an important class of biomolecules, playing essential roles in various living systems, and there is an ongoing demand for the efficient synthesis of peptide aldehydes. Herein, the authors report the electrooxidative ring-opening reaction via C‒N bond cleavage for the synthesis of unnatural peptide aldehydes.
- Xinyue Fang
- Yong Zeng
- Zhixiong Ruan