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Showing 1–9 of 9 results

Advanced filters: Author: Zhongyu Xiong Clear advanced filters

DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning

A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

Daya Guo
Dejian Yang
Zhen Zhang
ResearchOpen Access17 Sept 2025
Nature

Volume: 645, P: 633-638
RNA m⁵C oxidation by TET2 regulates chromatin state and leukaemogenesis

Chromatin-associated retrotransposon RNA 5-methylcytosine can be recognized by the methyl-CpG-binding-domain protein MBD6, which guides deubiquitination of nearby monoubiquitinated Lys119 of histone H2A to promote an open chromatin state in TET2-deficient cells.

Zhongyu Zou
Xiaoyang Dou
Chuan He
ResearchOpen Access02 Oct 2024
Nature

Volume: 634, P: 986-994
Pyrotinib and trastuzumab plus palbociclib and fulvestrant in HR+/HER2+ breast cancer patients with brain metastasis

Dongshao Chen
Fei Xu
Ruoxi Hong
ResearchOpen Access13 Jun 2024
npj Breast Cancer

Volume: 10, P: 1-7
CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis

Circular RNAs are expressed in the brain and show age-dependent expression patterns. Here the authors show the circGRIA1 is expressed in an age-dependent manner in the male macaque brain and serves a functional role in synaptic plasticity.

Kaiyu Xu
Ying Zhang
Jiali Li
ResearchOpen Access17 Jul 2020
Nature Communications

Volume: 11, P: 1-15
Mapping spatial transcriptome with light-activated proximity-dependent RNA labeling

A light-activated RNA labeling method was developed to determine spatial organization of a transcriptome and found that ribosomal proteins and oxidative phosphorylation pathway proteins are highly enriched at the outer mitochondrial membrane.

Pengchong Wang
Wei Tang
Peng Zou
Research07 Oct 2019
Nature Chemical Biology

Volume: 15, P: 1110-1119
Timing of initial collision and suturing processes in the Himalaya and Zagros

The collision of the Indian, Arabian and Eurasian plates formed the Tibetan and Iranian plateaus, but its timing and processes remain debated. This Review explores the evidence behind initial collision estimates and discusses the tectonic and geodynamic implications.

Chao Wang
Lin Ding
Muhammad Qasim
Reviews01 May 2025
Nature Reviews Earth & Environment

Volume: 6, P: 357-376
Cenozoic evolution of spring persistent rainfall in East Asia and North America driven by paleogeography

The emergence of the spring persistent rainfall in East Asia since the Miocene and its decline in North America was determined by paleogeographic events through mid-latitude Rossby wave trains, as revealed by climate models integrated with climate proxies.

Linqiang He
Tianjun Zhou
Wenxia Zhang
ResearchOpen Access27 Feb 2025
Communications Earth & Environment

Volume: 6, P: 1-8
Timing and mechanisms of Tibetan Plateau uplift

The geodynamic mechanisms and timing of Tibetan Plateau formation are debated, but are critical to understanding tectonic–climatic links. This Review discusses the stages of Tibetan Plateau evolution, and highlights that inherited weaknesses from pre-Cenozoic tectonic events influenced its variable surface uplift history.

Lin Ding
Paul Kapp
Chao Wang
Reviews28 Jul 2022
Nature Reviews Earth & Environment

Volume: 3, P: 652-667
Evolution of eastern Tibetan river systems is driven by the indentation of India

The evolution of river systems in the eastern Tibetan Plateau is controlled by the indentation of India at the large-scale but by fluvial self-organization at the scale of lower-order river networks, according to geomorphological analyses of river systems.

Yi Chen
Baosheng Wu
Bingshuai Li
ResearchOpen Access16 Dec 2021
Communications Earth & Environment

Volume: 2, P: 1-7