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Showing 1–4 of 4 results

Advanced filters: Author: Zi Wayne Sin Clear advanced filters

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
ZNF524 directly interacts with telomeric DNA and supports telomere integrity

ZNF524 is a newly described protein that binds to telomeres, the ends of linear chromosomes. ZNF524 promotes the presence of two members of the shelterin complex, TRF2/RAP1, at telomeres, and prevents genomic instability.

Hanna Braun
Ziyan Xu
Dennis Kappei
ResearchOpen Access12 Dec 2023
Nature Communications

Volume: 14, P: 1-17
A comparative pharmacogenomic analysis of three classic TCM prescriptions for coronary heart disease based on molecular network modeling

Ying-ying Zhang
Zi-de Zhao
Zhong Wang
Research12 Feb 2020
Acta Pharmacologica Sinica

Volume: 41, P: 735-744