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Showing 1–2 of 2 results
Advanced filters: Author: Zijuan Gu Clear advanced filters

  • In this Perspective, members of the Aging Biomarker Consortium outline the X-Age Project, an Aging Biomarker Consortium plan for building standardized aging clocks in China. The authors discuss the project roadmap and its aims of decoding aging heterogeneity, detecting accelerated aging early and evaluating geroprotective interventions.

    • Jiaming Li
    • Mengmeng Jiang
    • Guang-Hui Liu
    Reviews
    Nature Aging
    Volume: 5, P: 1669-1685

  • N6-methyladenosine (m6A) RNA modification regulates RNA metabolism, and has been implicated in immune regulation. Here, the authors show that the m6A methyltransferase, METTL3, translocates into the cytoplasm to increase viral RNA m6A modification, decreases viral ds RNA content, and thereby dampens the RIG/MDA5-induced anti-viral immunity.

    • Weinan Qiu
    • Qingyang Zhang
    • Pengyuan Yang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16