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Advanced filters: Author: Zohar Meir Clear advanced filters

Dissection of floral transition by single-meristem transcriptomes at high temporal resolution

Analyses of individual shoot meristem transcriptomes in wild-type and mutant tomato, at high temporal resolution, produce remarkably precise information about gene expression patterns during the transition from vegetative to floral growth that translates into genetic hierarchies.

Zohar Meir
Iris Aviezer
Yuval Eshed
Research16 Jun 2021
Nature Plants

Volume: 7, P: 800-813
Single-cell analysis of clonal maintenance of transcriptional and epigenetic states in cancer cells

Longitudinal single-cell analysis of transcription and DNA methylation dynamics in cancer cell lines suggests a clonally stable epigenetic memory. Colon cancer cells show a spectrum of epithelial-to-mesenchymal identities that seems independent of genetic variation.

Zohar Meir
Zohar Mukamel
Amos Tanay
Research29 Jun 2020
Nature Genetics

Volume: 52, P: 709-718
IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy

Straussman and colleagues undertake clonal analyses and show that drug tolerance to EGFR therapy in lung cancer cell populations is an inherited continuous trait that is determined by IRS1 phosphorylation.

Adi Jacob Berger
Elinor Gigi
Ravid Straussman
Research21 Oct 2021
Nature Cancer

Volume: 2, P: 1055-1070
Longitudinal symptom dynamics of COVID-19 infection

Although many COVID-19 cases are mild, most information about symptoms is derived from hospitalized patients. Here, the authors link self-reported symptom surveys to primary care data to describe the longitudinal dynamics of COVID-19 in non-hospitalized individuals.

Barak Mizrahi
Smadar Shilo
Eran Segal
ResearchOpen Access04 Dec 2020
Nature Communications

Volume: 11, P: 1-10
DISARM is a widespread bacterial defence system with broad anti-phage activities

A widespread anti-phage defence system, DISARM (defence island system associated with restriction–modification), is identified.

Gal Ofir
Sarah Melamed
Rotem Sorek
Research30 Oct 2017
Nature Microbiology

Volume: 3, P: 90-98