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Advanced filters: Author: Zongyang Gao Clear advanced filters

Comparison of chromatin accessibility landscapes during early development of prefrontal cortex between rhesus macaque and human

The evolution of epigenetic regulation of brain development in primates is not well understood. Here, the authors perform a comparative study of epigenetic dynamics of early prefrontal cortex development between human and rhesus macaque, finding divergent regulatory elements that may be related to cognitive capacity.

Xuelong Yao
Zongyang Lu
Jiang Liu
ResearchOpen Access06 Jul 2022
Nature Communications

Volume: 13, P: 1-15
Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6

Uba6 is an E1 enzyme that regulates numerous cellular processes by activating ubiquitin and FAT10 pathways. Here, the authors present crystal structures that illuminate Uba6 catalytic mechanisms and reveal inositol hexakisphosphate as a cofactor that modulates Uba6 activity.

Lingmin Yuan
Fei Gao
Shaun K. Olsen
ResearchOpen Access19 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Automatic assessment of adverse drug reaction reports with interactive visual exploration

Zongyang Gao
Yu Yang
Liang Zhou
ResearchOpen Access26 Apr 2022
Scientific Reports

Volume: 12, P: 1-11
Attain insensitivity to chlorine ions in magnesium alloys by impeding the diffusion process

Yuyang Chen
Guodong Fan
Xiaoqin Zeng
ResearchOpen Access13 Jan 2024
npj Materials Degradation

Volume: 8, P: 1-12

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