DNA computing and cryptography articles from across Nature Portfolio

Tracking raw materials is critical for securing global supply chains, but traditional tags lack in traceability and anticounterfeiting. The authors present a DNATag-based system for secure traceability, featuring error tolerance, mobile phone readability, and robust forgery protection.

Artificial simulated communication networks use biological and chemical molecules as information carriers to realize information transmission, but their design is challenging. Here, the authors report a DNA nanostructure recognition-based artificial molecular communication network, in which rectangular DNA origami nanostructures serve as nodes and their recognition as edges, and use it to construct various communication network topologies.

DNA data storage is a potential alternative to magnetic tape for archival storage purposes, promising substantial gains in information density. Here the authors investigate the susceptibility of DNA-encoded data to particle radiation damage by neutron irradiation and computational modeling, showing that particle radiation is not a significant contributor to data loss under typical storage conditions.

Targeting the files containing content-of-interest is a challenge in DNA data storage. Here, the authors develop a CRISPR-powered search engine to quantitatively identify the keyword in files stored in DNA.

DNA is an alternative to data storage materials for its durability, density, and energetics. Here the authors demonstrate the storage of digital information on DNA molecules using base-editing.

The extensive information capacity of DNA makes it an attractive alternative to traditional data storage. DNA-Aeon is a DNA data storage solution that can correct all error types commonly observed in DNA storage, while encoding data into sequences that meet user-defined constraints such as GC content, homopolymer length, and no undesired motifs.

A top-down computational method enables fabrication of DNA objects in any shape.

DNA square-root solver is biggest molecular computer yet.