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Tissue engineering is a branch of regenerative medicine, itself a branch of biomedical engineering. Tissue engineering and regenerative medicine are concerned with the replacement or regeneration of cells, tissues (the focus of tissue engineers) or organs to restore normal biological function.
A plant-derived photosynthetic nanoplatform uses light to reprogramme immune cells, reduce inflammation and repair joints in rheumatoid arthritis, offering a safe and bioinspired therapy
A spatiotemporally adaptive targeting strategy ensures sequentially reprogramming metabolism of inflammatory macrophages and senescent stem cells via intracellular NAD+ replenishment, accelerating bone and skin tissue regeneration.
Through binding mitochondrial ATP synthase, engineered nanomedicines rejuvenate aged bone stem cells and restore osteogenesis, reversing osteoporosis in mice and offering a potential senolytic therapy for skeletal ageing.
It is challenging to achieve scar-free repair of chronic wounds as they often feature the occurrence of multiple healing phases in an unpredictable and nonlinear manner. Here, the authors report a healing phase-adaptive regulating hydrogel that exhibits hierarchically delivering performance for programmed modulation of chronic infected wounds.
In a rabbit model of osteoarthritis, cartilage regeneration was promoted by a biodegradable implant that generates a piezoelectric response during physical exercise.
