Fig. 3: Proteomic profiles of cellular populations in different compartments of the microfluidic device, clustered according to cellular function.
a Summary of significant differences in proteomic profile between the astrocyte-only (red) and co-culture (green) compartments at 7 DIV. The proteomic profile was functionally categorised by the Gene Ontology (GO) pathway analysis. Significance was determined by an enrichment score of ≥1.3, protein count ≥15 and −log10P value ≥ 1.3. b Summary of significant differences in proteomic profile of the astrocyte-only (red) and co-culture (green) compartments as functionally categorised by the Reactome pathway analysis. Significance was determined by an enrichment score of ≥1.3, protein count ≥15 and −log10P value ≥ 1.3
