Fig. 7: Genetic alterations in spitzoid melanomas.
From: Spitz melanoma is a distinct subset of spitzoid melanoma
a Tiling plot highlighting the genetic landscape of spitzoid melanomas in our cohort, stratified by those with classical Spitz drivers, non-Spitz MAPK drivers, and those without an identifiable MAPK mutation. b Number of pathogenic mutations in each subset. c Proportion of cases with TERT promoter mutations. Note that those tumors with non-Spitz MAPK drivers demonstrated an increase in both the number of pathogenic mutations as well as TERT promoter mutations.
