Fig. 1: Study design and the PCNSL mutational landscape in Chinese patients.
From: Genomic landscape and molecular subtypes of primary central nervous system lymphoma
A Study design, including workflow and data composition for the discovery cohort and validation cohort. B Number and frequency of recurrent mutations. Gene‒sample matrix of recurrently mutated genes ranked by mutation frequency (n = 140). The total mutation density across the cohort is displayed at the top, with the variant allele fraction and trinucleotides at the bottom. C GISTIC2.0 results of significant recurrent focal amplifications (red) and deletions (blue). Genes affected by each focal event are annotated (n = 140). X-axis: plot of chromosomes; Y-axis: G score.
