Fig. 3 | Bone Research

Fig. 3

From: Two macrophages, osteoclasts and microglia: from development to pleiotropy

Fig. 3The alternative text for this image may have been generated using AI.

Horizontal pleiotropy of common genetic factors. Pyk2 signal could be a converging pathway of the genetic correlation between osteoporosis and Alzheimer’s disease (AD). Genetic variants in PTK2B are significantly associated with AD, body mass index, and bone mineral density suggesting that the two traits—osteoporosis and AD—could be linked by horizontal pleiotropy

Back to article page